Organoids-on-a-chip

SE Park, A Georgescu, D Huh - Science, 2019 - science.org
Recent studies have demonstrated an array of stem cell–derived, self-organizing miniature
organs, termed organoids, that replicate the key structural and functional characteristics of …

Nanoparticles in tissue engineering: applications, challenges and prospects

A Hasan, M Morshed, A Memic, S Hassan… - International journal …, 2018 - Taylor & Francis
Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …

Vascular tissue engineering: challenges and requirements for an ideal large scale blood vessel

CD Devillard, CA Marquette - Frontiers in bioengineering and …, 2021 - frontiersin.org
Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …

Precise tuning of facile one-pot gelatin methacryloyl (GelMA) synthesis

H Shirahama, BH Lee, LP Tan, NJ Cho - Scientific reports, 2016 - nature.com
Gelatin-methacryloyl (GelMA) is one of the most commonly used photopolymerizable
biomaterials in bio-applications. However, GelMA synthesis remains suboptimal, as its …

Distinct contributions of astrocytes and pericytes to neuroinflammation identified in a 3D human blood-brain barrier on a chip

A Herland, AD Van Der Meer, EA FitzGerald, TE Park… - PloS one, 2016 - journals.plos.org
Neurovascular inflammation is a major contributor to many neurological disorders, but
modeling these processes in vitro has proven to be difficult. Here, we microengineered a …

Metal‐based nanoparticles for bone tissue engineering

R Eivazzadeh‐Keihan, E Bahojb Noruzi… - Journal of Tissue …, 2020 - Wiley Online Library
Tissue is vital to the organization of multicellular organisms, because it creates the different
organs and provides the main scaffold for body shape. The quest for effective methods to …

Complex 3D‐printed microchannels within cell‐degradable hydrogels

KH Song, CB Highley, A Rouff… - Advanced Functional …, 2018 - Wiley Online Library
Abstract 3D‐printing is emerging as a technology to introduce microchannels into hydrogels,
for the perfusion of engineered constructs. Although numerous techniques have been …

Multiscale bioprinting of vascularized models

AK Miri, A Khalilpour, B Cecen, S Maharjan, SR Shin… - Biomaterials, 2019 - Elsevier
A basic prerequisite for the survival and function of three-dimensional (3D) engineered
tissue constructs is the establishment of blood vessels. 3D bioprinting of vascular networks …

From arteries to capillaries: approaches to engineering human vasculature

S Fleischer, DN Tavakol… - Advanced functional …, 2020 - Wiley Online Library
From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …

Applications of 3D bioprinting in tissue engineering and regenerative medicine

G Saini, N Segaran, JL Mayer, A Saini… - Journal of clinical …, 2021 - mdpi.com
Regenerative medicine is an emerging field that centers on the restoration and regeneration
of functional components of damaged tissue. Tissue engineering is an application of …