Background Previous reviews have shown that exposure to acute prolonged sitting can
have detrimental effects on several cardiovascular and cardiometabolic health markers …

Elevated pulse wave velocity (PWV) determined arterial stiffness is a prominent marker of
cardiovascular disease (CVD) risk. Exercise training delays the progression of CVD, but …

Sedentary behavior, particularly sitting, is ubiquitous in many contemporary societies. This is
a major societal concern considering the evidence for a strong association between sitting …

Prolonged uninterrupted sitting of> 3 h has been shown to acutely cause central and
peripheral cardiovascular dysfunction. However, individuals rarely sit uninterrupted for> 2 h …

Background Cardiotoxicity restricts anthracycline and trastuzumab treatment of Human
Epidermal Growth Factor Receptor 2 positive early breast cancer. Endothelial dysfunction …

This review proposes a biologically plausible working model for the relationship between
the 24-h activity cycle (24-HAC) and cardiovascular disease. The 24-HAC encompasses …

Regular exposure to uninterrupted prolonged sitting and the consumption of high-glycemic-
index (HGI) meals is independently associated with increased cardiovascular disease risk …

Exposure to uninterrupted prolonged sitting leads to macro-and microvascular
complications, which can contribute to increased cardiovascular disease risk. This study …

The acute reduction in peripheral arterial stiffness during reactive hyperemia is assumed to
be flow‐mediated; however, the mechanism remains unproven. We hypothesized that …

Purpose Prolonged sitting acutely increases arterial stiffness, with interruption strategies
only providing limited success in offsetting these rises. Acute aerobic exercise is a potent …