Asymmetric histone inheritance in asymmetrically dividing stem cells
Epigenetic mechanisms play essential roles in determining distinct cell fates during the
development of multicellular organisms. Histone proteins represent crucial epigenetic …
development of multicellular organisms. Histone proteins represent crucial epigenetic …
Stem cell ageing and non-random chromosome segregation
Adult stem cells maintain the mature tissues of metazoans. They do so by reproducing in
such a way that their progeny either differentiate, and thus contribute functionally to a tissue …
such a way that their progeny either differentiate, and thus contribute functionally to a tissue …
Tumor-initiating label-retaining cancer cells in human gastrointestinal cancers undergo asymmetric cell division
HW ** zebrafish
Asymmetric inheritance of sister chromatids has long been predicted to be linked to
discordant fates of daughter cells and even hypothesized to minimize accumulation of …
discordant fates of daughter cells and even hypothesized to minimize accumulation of …
SACK-expanded hair follicle stem cells display asymmetric nuclear Lgr5 expression with non-random sister chromatid segregation
We investigated the properties of clonally-expanded mouse hair follicle stem cells (HF-SCs)
in culture. The expansion method, suppression of asymmetric cell kinetics (SACK), is non …
in culture. The expansion method, suppression of asymmetric cell kinetics (SACK), is non …
[HTML][HTML] Wnt and the cancer niche: paracrine interactions with gastrointestinal cancer cells undergoing asymmetric cell division
HW **n, CM Ambe, S Ray, BK Kim, T Koizumi… - Journal of …, 2013 - ncbi.nlm.nih.gov
Objective: Stem-like cancer cells contribute to cancer initiation and maintenance. Stem cells
can self-renew by asymmetric cell division (ACD). ACD with non-random chromosomal …
can self-renew by asymmetric cell division (ACD). ACD with non-random chromosomal …