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Natural products: A lead for drug discovery and development
B Chopra, AK Dhingra - Phytotherapy Research, 2021 - Wiley Online Library
Natural products are used since ancient times in folklore for the treatment of various
ailments. Plant‐derived products have been recognized for many years as a source of …
ailments. Plant‐derived products have been recognized for many years as a source of …
Targeting NF-κB signaling pathway in cancer by dietary polyphenols
Being a transcription factor, NF-κB regulates gene expressions involving cell survival and
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …
An Insight Into the Modulatory Effects and Mechanisms of Action of Phyllanthus Species and Their Bioactive Metabolites on the Immune System
Phyllanthus species (family; Euphorbiaceae) have been intensively studied for their
immunomodulating effects due to their wide-ranging uses to treat immune-related diseases …
immunomodulating effects due to their wide-ranging uses to treat immune-related diseases …
Anti-inflammatory effects of four psilocybin-containing magic mushroom water extracts in vitro on 15-lipoxygenase activity and on lipopolysaccharide-induced …
SM Nkadimeng, CML Steinmann… - Journal of Inflammation …, 2021 - Taylor & Francis
Purpose During a pathological inflammation, macrophages are activated to produce
accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15 …
accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15 …
Critical review on anti‐inflammation effects of saponins and their molecular mechanisms
This review highlights the increasing interest in one of the natural compounds called
saponins, for their potential therapeutic applications in addressing inflammation which is a …
saponins, for their potential therapeutic applications in addressing inflammation which is a …
Traditional medicine herbs as natural product matrices in cancer chemoprevention: A trans pharmacological perspective (sco** review)
M Kalachaveedu, R Senthil… - Phytotherapy …, 2023 - Wiley Online Library
Emerging evidence on molecular biology related to tumors, inflammation, and immunity,
highlights their architectural commonality shifting cancer treatment paradigms toward more …
highlights their architectural commonality shifting cancer treatment paradigms toward more …
The Anti-Inflammatory Effects of Cannabis sativa Extracts on LPS-Induced Cytokines Release in Human Macrophages
Inflammation is the response of the innate immune system to any type of injury. Although
acute inflammation is critical for survival, dysregulation of the innate immune response leads …
acute inflammation is critical for survival, dysregulation of the innate immune response leads …
Deciphering psilocybin: Cytotoxicity, anti-inflammatory effects, and mechanistic insights
S Laabi, C LeMmon, C Vogel, M Chacon… - International …, 2024 - Elsevier
A decade of clinical research has indicated psilocybin's effectiveness in treating various
neuropsychiatric disorders, such as depression and substance abuse. The correlation …
neuropsychiatric disorders, such as depression and substance abuse. The correlation …
Exploring the potential of treating chronic liver disease targeting the PI3K/Akt pathway and polarization mechanism of macrophages
Y Yang, X Jia, M Qu, X Yang, Y Fang, X Ying, M Zhang… - Heliyon, 2023 - cell.com
Chronic liver disease is a significant public health issue that can lead to considerable
morbidity and mortality, imposing an enormous burden on healthcare resources …
morbidity and mortality, imposing an enormous burden on healthcare resources …
Ayurveda Rasayana as antivirals and immunomodulators: potential applications in COVID-19
Abstract Coronavirus disease (COVID-19) has been declared as a pandemic by the World
Health Organization with rapid spread across 216 countries. COVID-19 pandemic has left its …
Health Organization with rapid spread across 216 countries. COVID-19 pandemic has left its …