Homocysteine: its possible emerging role in at-risk population groups

E Azzini, S Ruggeri, A Polito - International journal of molecular sciences, 2020 - mdpi.com
Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

Current understandings in treating children with steroid-resistant nephrotic syndrome

JM Lee, A Kronbichler, JI Shin, J Oh - Pediatric Nephrology, 2021 - Springer
Steroid-resistant nephrotic syndrome (SRNS) remains a challenge for paediatric
nephrologists. SRNS is viewed as a heterogeneous disease entity including immune-based …

Mutations in the NUP93, NUP107 and NUP160 genes cause steroid-resistant nephrotic syndrome in Chinese children

Y Han, H Sha, Y Yang, Z Yu, L Zhou, Y Wang… - Italian Journal of …, 2024 - Springer
Background The variants of nucleoporins are extremely rare in hereditary steroid-resistant
nephrotic syndrome (SRNS). Most of the patients carrying such variants progress to end …

Nephrotic syndrome

E Rodriguez-Ballestas, J Reid-Adam - Pediatrics in Review, 2022 - publications.aap.org
Nephrotic syndrome (NS) encompasses a variety of disease processes leading to heavy
proteinuria and edema. Minimal change disease (MCD) remains the most common primary …

Diagnostic and prognostic value of soluble urokinase-type plasminogen activator receptor (suPAR) in focal segmental glomerulosclerosis and impact of detection …

W Winnicki, G Sunder-Plassmann, G Sengölge… - Scientific Reports, 2019 - nature.com
The plasma soluble urokinase-type plasminogen activator receptor (suPAR) is a biomarker
for focal segmental glomerulosclerosis (FSGS), but its value is under discussion because of …

Pediatric nephrotic syndrome: pharmacologic and nutrition management

KJ Hampson, ML Gay, ME Band - Nutrition in Clinical Practice, 2021 - Wiley Online Library
Nephrotic syndrome is a common kidney disease during childhood that is characterized by
alterations in glomerular filtration and leads to protein, fluid, and nutrient loss in the urine …

[HTML][HTML] Circulating permeability factors in focal segmental glomerulosclerosis: in vitro detection

ST Veissi, B Smeets, JAE van Wijk, R Classens… - Kidney International …, 2022 - Elsevier
Introduction The recurrence of proteinuria after kidney transplantation in patients with focal
segmental glomerulosclerosis (FSGS) is considered proof of the presence of circulating …

Potential molecular mechanisms of ephedra herb in the treatment of nephrotic syndrome based on network pharmacology and molecular docking

T Yao, Q Wang, S Han, Y Lu, Y Xu… - BioMed Research …, 2022 - Wiley Online Library
Objective. To explore the possible mechanisms of Ephedra herb (EH) in the treatment of
nephrotic syndrome (NS) by using network pharmacology and molecular docking in this …

B-cell activating factor (BAFF) and its receptors' expression in pediatric nephrotic syndrome is associated with worse prognosis

J Forero-Delgadillo, V Ochoa, JM Restrepo… - PLoS …, 2022 - journals.plos.org
Aim Immune pathogenesis of nephrotic syndrome (NS) is not completely understood. We
aimed to evaluate the expression of B-cell activating factor (BAFF) and its receptors in renal …

Quercetin-targeted AKT1 regulates the Raf/MEK/ERK signaling pathway to protect against doxorubicin-induced nephropathy in mice

W Yufang, L Mingfang, H Nan, W Tingting - Tissue and Cell, 2023 - Elsevier
Background Doxorubicin is an anthracycline antitumor agent commonly used in clinical
practice, which has some nephrotoxicity and is often used to establish mouse models of …