Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …

Cocrystallization has been recognized as one of the most successful approaches to address
the stability problems of active pharmaceutical ingredients (APIs) in the past few decades …

L-menthol is one of the most important flavoring additives with abundant plant sources. The
distinctive odor, cooling characteristic, and diversified biological activities attribute to its …

Elderberry (Sambucus nigra L.) is a widespread deciduous shrub, of which the fruits
(elderberries) are used in the food industry to produce different types of dietary supplement …

Organic cocrystals based on H-bonding as well as π-stacking interactions between 4, 4′-
bipyridine–pyromellitic acid (1) and 4, 4′-bipyridine–phthalic acid (2) are reported …

In crystal engineering, cocrystallization has become one of the preferred methods for
improving the physicochemical properties of active pharmaceutical ingredients (APIs). The …

The pharmaceutical agent theophylline (THEO) is primarily used as a bronchodilator and is
commercially available in both tablet and liquid dosage forms. THEO is highly hygroscopic …

The separation of chiral compounds into their enantiomers is widely used in the
pharmaceutical industry. Two types of environmentally benign tartaric acid derivatives, O …

Two bipyridine isomers (2, 2′-and 4, 4′-), used as coformers and ligands in coordination
chemistry, were subjected to solid form screening and crystal structure prediction. One …

We examine the reliability of lattice energies (and by inference, intermolecular interaction
energies) estimated from experimental electron densities. Based on the modest number of …