Antibiotic resistance is a serious global health concern that may have significant social and
financial consequences. Methicillin-resistant Staphylococcus aureus (MRSA) infection is …

Shotgun metagenomics studies have improved our understanding of microbial population
dynamics and have revealed significant contributions of microbes to gut homeostasis. They …

Bacteria can exceptionally evolve and develop pathogenic features making it crucial to
determine novel pathogenic proteins for specific therapeutic interventions. Therefore, we …

Biofilms are thought to be sinks for antibiotic resistance genes (ARGs) and nanoparticles
(NPs), however, studies on the interactions between NPs and ARGs in biofilms are limited …

Staphylococcus aureus is a common cause of severe infections, and its widespread
antibiotic resistance necessitates search for alternative therapies, such as inhibition of …

The BL19U2 at the Shanghai Synchrotron Radiation Facility is a small-angle X-ray
scattering beamline dedicated to structural studies pertaining to biological macromolecules …

In human pathogenic fungi, receiver domains from hybrid histidine kinases (hHK) have to
recognize one HPt. To understand the recognition mechanism, we have assessed …

Acinetobacter baumannii is an insidious emerging nosocomial pathogen that has developed
resistance to all available antimicrobials, including the last resort antibiotic, colistin. Colistin …

Introduction Acinetobacter baumannii PmrAB is a crucial two-component regulatory system
(TCS) that plays a vital role in conferring resistance to polymyxin. PmrA, a response …

Two component signaling system ArlRS (Autolysis-related locus) regulates adhesion, biofilm
formation and virulence in methicillin resistant Staphylococcus aureus. It consists of a …