Spray drying formulation of amorphous solid dispersions

A Singh, G Van den Mooter - Advanced drug delivery reviews, 2016 - Elsevier
Spray drying is a well-established manufacturing technique which can be used to formulate
amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water …

Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations

A Paudel, ZA Worku, J Meeus, S Guns… - International journal of …, 2013 - Elsevier
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Pharmaceutical Particle Engineering via Spray Drying

R Vehring - Pharmaceutical research, 2008 - Springer
This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …

Freeze-drying of nanoparticles: formulation, process and storage considerations

W Abdelwahed, G Degobert, S Stainmesse… - Advanced drug delivery …, 2006 - Elsevier
Freeze-drying has been considered as a good technique to improve the long-term stability of
colloidal nanoparticles. The poor stability in an aqueous medium of these systems forms a …

Microencapsulation: industrial appraisal of existing technologies and trends

S Gouin - Trends in food science & technology, 2004 - Elsevier
Controlled release of food ingredients at the right place and the right time is a key
functionality that can be provided by microencapsulation. A timely and targeted release …

Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways

BA Kerwin - Journal of pharmaceutical sciences, 2008 - Elsevier
ABSTRACT Polysorbates 20 and 80 (Tween® 20 and Tween® 80) are used in the
formulation of biotherapeutic products for both preventing surface adsorption and as …

Particle engineering for pulmonary drug delivery

AHL Chow, HHY Tong, P Chattopadhyay… - Pharmaceutical …, 2007 - Springer
With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

Progress in spray-drying of protein pharmaceuticals: Literature analysis of trends in formulation and process attributes

JT Pinto, E Faulhammer, J Dieplinger, M Dekner… - Drying …, 2021 - Taylor & Francis
Spray-drying is an inherently continuous and well-established industrial drying process. It
can accelerate manufacturing of biopharmaceuticals and vaccine products, resulting in both …

Dry powders for oral inhalation free of lactose carrier particles

AM Healy, MI Amaro, KJ Paluch, L Tajber - Advanced drug delivery reviews, 2014 - Elsevier
Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …

[BUKU][B] Surfactants and polymers in drug delivery

M Malmsten - 2002 - taylorfrancis.com
This reference features the latest findings surrounding the physicochemical aspects of
surfactant and polymer systems to facilitate the design and understanding of novel and …