Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors

M Berk, F Kapczinski, AC Andreazza, OM Dean… - … & biobehavioral reviews, 2011 - Elsevier
There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that …

M Maes, P Galecki, YS Chang, M Berk - Progress in Neuro …, 2011 - Elsevier
This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …

[HTML][HTML] Is depression associated with increased oxidative stress? A systematic review and meta-analysis

CN Black, M Bot, PG Scheffer, P Cuijpers… - …, 2015 - Elsevier
Background It has been suggested that depressed persons have increased oxidative stress
and decreased anti-oxidant defences. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) and F2 …

Oxidative stress and psychological disorders

S Salim - Current neuropharmacology, 2014 - ingentaconnect.com
Oxidative stress is an imbalance between cellular production of reactive oxygen species and
the counteracting antioxidant mechanisms. The brain with its high oxygen consumption and …

[HTML][HTML] Clinical trials of N-acetylcysteine in psychiatry and neurology: a systematic review

J Slattery, N Kumar, L Delhey, M Berk, O Dean… - Neuroscience & …, 2015 - Elsevier
N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

O Dean, F Giorlando, M Berk - Journal of Psychiatry and Neuroscience, 2011 - jpn.ca
There is an expanding field of research investigating the benefits of alternatives to current
pharmacological therapies in psychiatry. N-acetylcysteine (NAC) is emerging as a useful …

The promise of N-acetylcysteine in neuropsychiatry

M Berk, GS Malhi, LJ Gray, OM Dean - Trends in pharmacological sciences, 2013 - cell.com
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of
multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant …

The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …