The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

The trigeminal nerve (V) is the fifth and largest of all cranial nerves, and it is responsible for
detecting sensory stimuli that arise from the craniofacial area. The nerve is divided into three …

Trigeminal Neuralgia Trigeminal neuralgia is manifested by severe, paroxysmal facial pain.
The classical type involves compression of the trigeminal nerve root. Sodium-channel …

Over the past 20 years, clinical and preclinical studies point to the anterior cingulate cortex
(ACC) as a site of interest for several neurological and psychiatric conditions. The ACC …

The relationship between pain and depression is thought to be bidirectional and the
underlying neurobiology 'shared'between the two conditions. However, these claims are …

Objective To characterize the functional brain changes involved in δ-9-tetrahydrocannabinol
(THC) modulation of chronic neuropathic pain. Methods Fifteen patients with chronic …

Objective This study aimed to combine voxel-based morphometry, deformation-based
morphometry, and surface-based morphometry to analyze gray matter volume and cortex …

Classic trigeminal neuralgia (CTN) is a neuropathic pain disorder displaying spontaneously
stabbing or electric shock-like paroxysms in the face. Previous research suggests structural …

Chronic pain has widespread, detrimental effects on the human nervous system and its
prevalence and burden increase with age. Machine learning techniques have been applied …

Background Despite evidently distinct symptoms, tension-type headache (TTH) and
migraine are highly comorbid and exhibit many similarities in clinical practice. The purpose …