The functional impact of mitochondrial structure across subcellular scales
Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …
mitochondria varies from cell to cell depending on the relative demands for energy …
Mitochondrial dysfunction in diabetic kidney disease
Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …
disease, which are major risk factors for cardiovascular disease and death. Despite this …
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
INTRODUCTION There has been an explosion of interest in the role of cell death pathways
and damage-associated molecular pattern (DAMP) signaling in sha** inflammatory and …
and damage-associated molecular pattern (DAMP) signaling in sha** inflammatory and …
Mitochondrial dynamics controls T cell fate through metabolic programming
Summary Activated effector T (TE) cells augment anabolic pathways of metabolism, such as
aerobic glycolysis, while memory T (TM) cells engage catabolic pathways, like fatty acid …
aerobic glycolysis, while memory T (TM) cells engage catabolic pathways, like fatty acid …
Multiple cell death modalities and their key features
Cell death, as a final cellular decision which is reached following complex communications,
represents a critical process with which to maintain organismic homeostasis. Different …
represents a critical process with which to maintain organismic homeostasis. Different …
The nature of the mechanical bond: from molecules to machines
CJ Bruns, JF Stoddart - 2016 - books.google.com
" The story is told by THE inventor-pioneer-master in the field and is accompanied by
amazing illustrations...[it] will become an absolute reference and a best seller in chemistry!" …
amazing illustrations...[it] will become an absolute reference and a best seller in chemistry!" …
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Mitochondria undergo fragmentation in response to electron transport chain (ETC) poisons
and mitochondrial DNA–linked disease mutations, yet how these stimuli mechanistically …
and mitochondrial DNA–linked disease mutations, yet how these stimuli mechanistically …
Mechanisms of muscle insulin resistance and the cross‐talk with liver and adipose tissue
SC da Silva Rosa, N Nayak, AM Caymo… - Physiological …, 2020 - Wiley Online Library
Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth
JA Kashatus, A Nascimento, LJ Myers, A Sher… - Molecular cell, 2015 - cell.com
Ras is mutated in up to 30% of cancers, including 90% of pancreatic ductal
adenocarcinomas, causing it to be constitutively GTP-bound, and leading to activation of …
adenocarcinomas, causing it to be constitutively GTP-bound, and leading to activation of …
[HTML][HTML] Fullerene: biomedical engineers get to revisit an old friend
In 1985, the serendipitous discovery of fullerene triggered the research of carbon structures
into the world of symmetric nanomaterials. Consequently, Robert F. Curl, Harold W. Kroto …
into the world of symmetric nanomaterials. Consequently, Robert F. Curl, Harold W. Kroto …