More than a decade ago, spinal-cord injury meant confinement to a wheelchair and a
lifetime of medical comorbidity. The physician's armamentarium of treatments was very …

Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Huntingtin is a 350-kilodalton protein of unknown function that is mutated in Huntington's
disease (HD), a neurodegenerative disorder. The mutant protein is presumed to acquire a …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat
expansion in the gene encoding for huntingtin protein. A lot has been learned about this …

Recent progress shows that neurons suitable for transplantation can be generated from
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …

Huntington's disease (HD) is an autosomal neurodegenerative disease that is characterized
by an excessive number of CAG trinucleotide repeats within the huntingtin gene (HTT). HD …

Huntington's disease (HD) is the most common monogenic neurodegenerative disease and
the commonest genetic dementia in the developed world. With autosomal dominant …

Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …

Cerebral plasticity, which is the dynamic potential of the brain to reorganize itself during
ontogeny, learning, or following damage, has been widely studied in the last decade, in …

Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …