[HTML][HTML] Targeting Metabolic–Redox Nexus to Regulate Drug Resistance: From Mechanism to Tumor Therapy
Y Wang, J He, S Lian, Y Zeng, S He, J Xu, L Luo… - Antioxidants, 2024 - mdpi.com
Drug resistance is currently one of the biggest challenges in cancer treatment. With the
deepening understanding of drug resistance, various mechanisms have been revealed …
deepening understanding of drug resistance, various mechanisms have been revealed …
A review on carbon nanotubes family of nanomaterials and their health field
The use of carbon nanotubes (CNTs), which are nanometric materials, in pathogen
detection, protection of environments, food safety, and in the diagnosis and treatment of …
detection, protection of environments, food safety, and in the diagnosis and treatment of …
Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application
Multidrug resistance in breast cancer and the associated side‐effects of anticancer therapies
are significant hurdles in chemotherapy‐based treatment. Biodegradable polymeric nano …
are significant hurdles in chemotherapy‐based treatment. Biodegradable polymeric nano …
Apigenin loaded lipoid–PLGA–TPGS nanoparticles for colon cancer therapy: Characterization, sustained release, cytotoxicity, and apoptosis pathways
Colon cancer (CC) is one of major causes of mortality and affects the socio-economic status
world-wide. Therefore, develo** a novel and efficient delivery system is needed for CC …
world-wide. Therefore, develo** a novel and efficient delivery system is needed for CC …
Exploration of the inhibition action of TPGS on tumor cells and its combined use with chemotherapy drugs
L Tang, K Huang, W Jiang, L Fu, R Zhang, L Shen… - Drug Delivery, 2023 - Taylor & Francis
D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS) is a commonly used
nonionic surfactant used as a pharmaceutical carrier in different drug delivery systems …
nonionic surfactant used as a pharmaceutical carrier in different drug delivery systems …
[HTML][HTML] Emerging frontiers in drug delivery with special focus on novel techniques for targeted therapies
L Yu, S Liu, S Jia, F Xu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The management and treatment of disease are achieved via the use of pharmacologically
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
A QbD approach to design and to optimize the self-emulsifying resveratrol–phospholipid complex to enhance drug bioavailability through lymphatic transport
Highlights The FTIR, DSC, and the XRD characterization confirmed the successful complex
formation between resveratrol and phospholipid. The optimal SEDDS formulation exhibited …
formation between resveratrol and phospholipid. The optimal SEDDS formulation exhibited …
Nanostructured lipid carrier–based gel for repurposing simvastatin in localized treatment of breast cancer: formulation design, development, and in vitro and in vivo …
Simvastatin (SMV) is noticed as a repurposed candidate to be effective against breast
cancer (BC). However, poor solubility, dose-limiting toxicities, and side effects are critical …
cancer (BC). However, poor solubility, dose-limiting toxicities, and side effects are critical …
Self-assembled mixed nanomicelles based hydrogel for enhanced transdermal bioavailability of allopurinol in gout therapy: In vitro and In vivo evaluation
R Mirza, KU Shah, AU Rehman - Journal of Drug Delivery Science and …, 2024 - Elsevier
Allopurinol (ALP), a preferred first line medication for the treatment of gout and
hyperuricemia, exhibits poor solubility, a short half-life, and undergoes the hepatic first-pass …
hyperuricemia, exhibits poor solubility, a short half-life, and undergoes the hepatic first-pass …
Nanoarchitectonics of doxycycline-loaded vitamin E–D-α-tocopheryl polyethylene glycol 1000 succinate micelles for ovarian cancer stem cell treatment
Aim: This study aim to develop doxycycline within the D-α-tocopheryl polyethylene glycol
1000 succinate micelle platform as an anticancer stem cell agent. Materials & methods: The …
1000 succinate micelle platform as an anticancer stem cell agent. Materials & methods: The …