[HTML][HTML] PTX3, a humoral pattern recognition molecule, in innate immunity, tissue repair, and cancer

C Garlanda, B Bottazzi, E Magrini… - Physiological …, 2018 - journals.physiology.org
Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern
recognition molecule conserved in evolution which acts as a key component of humoral …

An integrated view of humoral innate immunity: pentraxins as a paradigm

B Bottazzi, A Doni, C Garlanda… - Annual review of …, 2009 - annualreviews.org
The innate immune system consists of a cellular and a humoral arm. Pentraxins (eg, the
short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the …

Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation

C Cunha, F Aversa, JF Lacerda, A Busca… - … England Journal of …, 2014 - Mass Medical Soc
Background The soluble pattern-recognition receptor known as long pentraxin 3 (PTX3) has
a nonredundant role in antifungal immunity. The contribution of single-nucleotide …

The long pentraxin PTX3 as a link between innate immunity, tissue remodeling, and cancer

A Doni, M Stravalaci, A Inforzato, E Magrini… - Frontiers in …, 2019 - frontiersin.org
The innate immune system comprises a cellular and a humoral arm. Humoral pattern
recognition molecules include complement components, collectins, ficolins, and pentraxins …

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

S Jaillon, G Peri, Y Delneste, I Frémaux… - The Journal of …, 2007 - rupress.org
The long pentraxin (PTX) 3 is produced by macrophages and myeloid dendritic cells in
response to Toll-like receptor agonists and represents a nonredundant component of …

Steroid hormone receptor expression and function in microglia

A Sierra, A Gottfried‐Blackmore, TA Milner… - Glia, 2008 - Wiley Online Library
Steroid hormones such as glucocorticoids and estrogens are well‐known regulators of
peripheral immune responses and also show anti‐inflammatory properties in the brain …

Innate Immunity to Aspergillus Species

SJ Park, B Mehrad - Clinical microbiology reviews, 2009 - journals.asm.org
All humans are continuously exposed to inhaled Aspergillus conidia, yet healthy hosts clear
the organism without develo** disease and without the development of antibody-or cell …

[HTML][HTML] Molecular insight into pentraxin-3: Update advances in innate immunity, inflammation, tissue remodeling, diseases, and drug role

H Zhang, R Wang, Z Wang, W Wu, N Zhang… - Biomedicine & …, 2022 - Elsevier
Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …

Structural recognition and functional activation of FcγR by innate pentraxins

J Lu, LL Marnell, KD Marjon, C Mold, TW Du Clos… - Nature, 2008 - nature.com
Pentraxins are a family of ancient innate immune mediators conserved throughout evolution.
The classical pentraxins include serum amyloid P component (SAP) and C-reactive protein …

Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review

CA Croft, L Culibrk, MM Moore, SJ Tebbutt - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …