The main protease (Mpro) is the key enzyme of nCOVID-19 and plays a decisive role that
makes it an attractive drug target. Multiple analysis of crystal structures reveals the presence …

Molecular dynamics (MD) simulations were used to investigate the binding of four ligands to
the Val122Ile mutant of the protein transthyretin. Dissociation, misfolding, and subsequent …

Human transthyretin (hTTR) is a multifunctional protein that is involved in several
neurodegenerative diseases. Besides the transportation of thyroxin and vitamin A, it is also …

Among the 23 different fibril proteins described in human amyloidosis, transthyretin is
associated with the most common hereditary form of the disease and its knowledge is …

Transthyretin (TTR), also known as prealbumin, is a highly conserved protein found in
several vertebrate species. Dissociation of TTR tetramer followed by aggregation and …

There has been much progress in our understanding of transthyretin (TTR)-related
amyloidosis including familial amyloidotic polyneuropathy (FAP), senile systemic …

Protein folding is a longstanding challenge in structural biology. No one knows how to
predict the correct native structure or folding of a protein from the primary amino acid …

Human transthyretin (hTTR) is a multifunctional protein involved in several amyloidogenic
diseases. Besides transportation of thyroxin and vitamin-A, its role towards the catalysis of …

Abstract Fungal endo-1, 4-β-xylanases (EC3. 2.1. 8), because of their widespread industrial
applications have become one of the most researched industrial enzymes in recent times …

Hereditary transthyretin amyloidosis (hATTR) is a progressive, autosomal dominant,
multisystem disease with incomplete and age-related penetrance. The disease presents …