Cough hypersensitivity and chronic cough

KF Chung, L McGarvey, WJ Song, AB Chang… - Nature Reviews …, 2022 - nature.com
Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …

Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses

WJ Song, CKM Hui, JH Hull, SS Birring… - The Lancet …, 2021 - thelancet.com
Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection …

Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two …

LP McGarvey, SS Birring, AH Morice, PV Dicpinigaitis… - The Lancet, 2022 - thelancet.com
Background Gefapixant is an oral P2X 3 receptor antagonist that has previously shown
efficacy and safety in refractory chronic cough and unexplained chronic cough. We therefore …

Epidemiology, clinical presentation, pathophysiology, and management of long COVID: an update

S Su, Y Zhao, N Zeng, X Liu, Y Zheng, J Sun… - Molecular …, 2023 - nature.com
The increasing number of coronavirus disease 2019 (COVID-19) infections have highlighted
the long-term consequences of severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Chronic cough: new insights and future prospects

A Morice, P Dicpinigaitis, L McGarvey… - European Respiratory …, 2021 - Eur Respiratory Soc
Chronic cough is defined in adults as a cough that lasts for≥ 8 weeks. When it proves
intractable to standard-of-care treatment, it can be referred to as refractory chronic cough …

Natural history, phenotypic spectrum, and discriminative features of multisystemic RFC1 disease

A Traschütz, A Cortese, S Reich, N Dominik, J Faber… - Neurology, 2021 - AAN Enterprises
Objective To delineate the full phenotypic spectrum, discriminative features, piloting
longitudinal progression data, and sample size calculations of replication factor complex …

Management of functional communication, swallowing, cough and related disorders: consensus recommendations for speech and language therapy

J Baker, C Barnett, L Cavalli, M Dietrich… - Journal of Neurology …, 2021 - jnnp.bmj.com
Communication problems (eg, dysphonia, dysfluency and language and articulation
disorders), swallowing disorders (dysphagia and globus), cough and upper airway …

Palliative care early in the care continuum among patients with serious respiratory illness: an official ATS/AAHPM/HPNA/SWHPN policy statement

DR Sullivan, AS Iyer, S Enguidanos… - American Journal of …, 2022 - atsjournals.org
Background: Patients with serious respiratory illness and their caregivers suffer
considerable burdens, and palliative care is a fundamental right for anyone who needs it …

Swiss recommendations for the follow-up and treatment of pulmonary long COVID

M Funke-Chambour, PO Bridevaux, CF Clarenbach… - Respiration, 2021 - karger.com
Introduction: Emerging evidence suggests that long-term pulmonary symptoms and
functional impairment occurs in a proportion of individuals following SARS-CoV-2 infection …

Efficacy and tolerability of gefapixant for treatment of refractory or unexplained chronic cough: a systematic review and dose-response meta-analysis

E Kum, M Patel, N Diab, M Wahab, D Zeraatkar… - Jama, 2023 - jamanetwork.com
Importance Gefapixant represents an emerging therapy for patients with refractory or
unexplained chronic cough. Objective To evaluate the efficacy and tolerability of gefapixant …