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The lamin protein family
The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the
inside of the nuclear membrane, where they provide a platform for the binding of proteins …
inside of the nuclear membrane, where they provide a platform for the binding of proteins …
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
Over the past few years it has become evident that the intermediate filament proteins, the
types A and B nuclear lamins, not only provide a structural framework for the nucleus, but …
types A and B nuclear lamins, not only provide a structural framework for the nucleus, but …
A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
Abbreviations used in this paper: BAT, biotin acceptor tag; bioAMP, biotinoyl-5-AMP; BioID,
proximity-dependent biotin identification; BirA*, BirA-R118G; INM, inner nuclear membrane; …
proximity-dependent biotin identification; BirA*, BirA-R118G; INM, inner nuclear membrane; …
Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence
In metazoans, the nuclear lamina is thought to play an important role in the spatial
organization of interphase chromosomes, by providing anchoring sites for large genomic …
organization of interphase chromosomes, by providing anchoring sites for large genomic …
Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction
Background—Inflammatory mechanisms have been proposed to be important in heart
failure (HF), and cytokines have been implicated to add to the progression of HF. However, it …
failure (HF), and cytokines have been implicated to add to the progression of HF. However, it …
Nuclear lamins
T Dechat, SA Adam, P Taimen… - Cold Spring …, 2010 - cshperspectives.cshlp.org
The nuclear lamins are type V intermediate filament proteins that are critically important for
the structural properties of the nucleus. In addition, they are involved in the regulation of …
the structural properties of the nucleus. In addition, they are involved in the regulation of …
Real-time single-molecule imaging of the infection pathway of an adeno-associated virus
G Seisenberger, MU Ried, T Endress, H Buning… - Science, 2001 - science.org
We describe a method, based on single-molecule imaging, that allows the real-time
visualization of the infection pathway of single viruses in living cells, each labeled with only …
visualization of the infection pathway of single viruses in living cells, each labeled with only …
The A-and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription
The nuclear lamins function in the regulation of replication, transcription, and epigenetic
modifications of chromatin. However, the mechanisms responsible for these lamin functions …
modifications of chromatin. However, the mechanisms responsible for these lamin functions …
Nuclear lamins: building blocks of nuclear architecture
Nuclear lamins were initially identified as the major components of the nuclear lamina, a
proteinaceous layer found at the interface between chromatin and the inner nuclear …
proteinaceous layer found at the interface between chromatin and the inner nuclear …
Nuclear lamins: laminopathies and their role in premature ageing
It has been demonstrated that nuclear lamins are important proteins in maintaining cellular
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …
as well as nuclear integrity, and in maintaining chromatin organization in the nucleus …