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Virulence factors of Leishmania parasite: Their paramount importance in unraveling novel vaccine candidates and therapeutic targets
Leishmaniasis is a neglected tropical disease and remains a global concern for healthcare.
It is caused by an opportunistic protozoan parasite belonging to the genus Leishmania and …
It is caused by an opportunistic protozoan parasite belonging to the genus Leishmania and …
Insights into the drug screening approaches in leishmaniasis
Leishmaniasis, a tropically neglected disease, is responsible for the high mortality and
morbidity ratio in poverty-stricken areas. Currently, no vaccine is available for the complete …
morbidity ratio in poverty-stricken areas. Currently, no vaccine is available for the complete …
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
[HTML][HTML] Leishmania Vesicle-Depleted Exoproteome: What, Why, and How?
S Esteves, I Costa, S Luelmo, N Santarém… - Microorganisms, 2022 - mdpi.com
Leishmaniasis, a vector-borne parasitic protozoan disease, is among the most important
neglected tropical diseases. In the absence of vaccines, disease management is …
neglected tropical diseases. In the absence of vaccines, disease management is …
[HTML][HTML] Experimental strategies to explore drug action and resistance in kinetoplastid parasites
Kinetoplastids are the causative agents of leishmaniasis, human African trypanosomiasis,
and American trypanosomiasis. They are responsible for high mortality and morbidity in …
and American trypanosomiasis. They are responsible for high mortality and morbidity in …
[HTML][HTML] Applied proteomics in 'one health'
'One Health'summarises the idea that human health and animal health are interdependent
and bound to the health of ecosystems. The purpose of proteomics methodologies and …
and bound to the health of ecosystems. The purpose of proteomics methodologies and …
Leishmania (L.) amazonensis LaLRR17 increases parasite entry in macrophage by a mechanism dependent on GRP78
MS Peña, FHF Tang, FA de Lima Franco… - Parasitology, 2023 - cambridge.org
Leishmaniases affect 12 million people worldwide. They are caused by Leishmania spp.,
protozoan parasites transmitted to mammals by female phlebotomine flies. During the life …
protozoan parasites transmitted to mammals by female phlebotomine flies. During the life …
Proteomic Analysis of the Promastigote Secretome of Seven Leishmania Species
J Pissarra, J Pagniez, E Petitdidier… - Journal of Proteome …, 2021 - ACS Publications
Leishmaniasis is one of the most impactful parasitic diseases worldwide, endangering the
lives of 1 billion people every year. There are 20 different species of Leishmania able to …
lives of 1 billion people every year. There are 20 different species of Leishmania able to …
Differentially modulated proteins associated with Leishmaniasis—a systematic review of in-vivo and in-vitro studies
R Ranjan, P Das, S Vijayakumar - Molecular Biology Reports, 2020 - Springer
High-throughput proteomic technologies are widely used for understanding the disease
mechanism, drug-resistant mechanism, and to identify drug targets and markers for …
mechanism, drug-resistant mechanism, and to identify drug targets and markers for …
[HTML][HTML] Proteomic Analysis of Leishmania donovani Membrane Components Reveals the Role of Activated Protein C Kinase in Host-Parasite Interaction
Visceral leishmaniasis (VL), mainly caused by the Leishmania donovani parasitic infection,
constitutes a potentially fatal disease, for which treatment is primarily dependent on …
constitutes a potentially fatal disease, for which treatment is primarily dependent on …