Objective To determine the association between exposure to radiotherapy for the treatment
of prostate cancer and subsequent second malignancies (second primary cancers). Design …

Context Radiotherapy used for treating localized prostate cancer is effective at prolonging
cancer-specific and overall survival. Still, acute and late pelvic toxicities are a concern, with …

The development of a radiation induced second primary cancer (SPC) is one the most
serious long term consequences of successful cancer treatment. This review aims to …

We investigated whether prostate cancer patients treated with external beam radiation
therapy (EBRT) have a higher cumulative incidence of secondary cancer compared with …

Study Type–Therapy (case series) Level of Evidence 4 What's known on the subject? and
What does the study add? Radiation Therapy for prostate cancer can increase the risk for …

Risks of radiation-induced second primary cancer following prostate radiotherapy using 3D-
conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), volumetric …

Radiation therapy along with chemotherapy and surgery are the three main treatment
modalities used in oncology. The main disadvantage of radiotherapy is the fact that it affects …

Radiotherapy (RT) for prostate cancer has been associated with an increased risk for the
development of bladder cancer. We aimed to integrate clinical and genomic data to better …

Purpose To assess the risk of second primary cancer (SPC) after [125I] iodine prostate
cancer brachytherapy compared with prostatectomy and the general population. Patients …

In the era of modern radiation therapy, the compromise between the reductions in
deterministic radiation-induced toxicities through highly conformal devices may be impacting …