Periprosthetic joint infection (PJI) remains a devastating complication after total joint
arthroplasty. Bacteria involved in these infections are notorious for adhering to foreign …

Background Thorough irrigation and debridement using an irrigation solution is a well-
established treatment for both acute and chronic periprosthetic joint infections (PJIs). In the …

Introduction: Chlorhexidine gluconate (CHX) is widely used as a preoperative surgical skin-
preparation solution and intra-wound irrigation agent, with excellent efficacy against wide …

Wound care remains a challenge in healthcare. This work aimed to develop a new polyvinyl
alcohol (PVA)/chitosan (Ch) based wound dressing able to ensure protection, hydration and …

The Second International Consensus Meeting on Orthopedic Infections was held in
Philadelphia, Pennsylvania, in July 2018. Over 800 international experts from all 9 …

Background The occurrence of surgical site infections (SSIs) is associated with increased
risk of mortality, development of other infections, and the need for reintervention, posing a …

Irrigation and debridement in the treatment of periprosthetic joint infection (PJI) serve an
integral role in the eradication of bacterial burden and subsequent re-infection rates …

Biomaterial‐associated infections (BAIs) pose significant challenges in modern medical
technologies, being a major postoperative complication and leading cause of implant failure …

A projected increased use of total joint arthroplasties will naturally result in a related
increase in the number of prosthetic joint infections (PJIs). Suppression of the local peri …

Chlorhexidine is used widely to prevent the spread of bacteria in the hospital environment.
However, bacteria are increasingly becoming tolerant to chlorhexidine. Here we …