Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …

Emerging evidence indicates that Ca2+ is a vital factor in modulating the pathogenesis of
Alzheimer's disease (AD). In healthy neurons, Ca2+ concentration is balanced to maintain a …

The microtubule‐associated protein tau has primarily been associated with axonal location
and function; however, recent work shows tau release from neurons and suggests an …

As a pivotal player in regulating sodium (Na+) and calcium (Ca 2+) homeostasis and
signalling in excitable cells, the Na+/Ca 2+ exchanger (NCX) is involved in many …

Spatial and temporal control of calcium (Ca 2+) levels is essential for the background
rhythms and responses of living cells to environmental stimuli. Whatever other regulators a …

Synapse dysfunction is an integral feature of Alzheimer's disease (AD) pathophysiology. In
fact, prodromal manifestation of structural and functional deficits in synapses much prior to …

Background and Purpose SKF 96365 is well known for its suppressing effect on human
glioblastoma growth by inhibiting pre‐activated transient receptor potential canonical …

Although the amyloid-β1–42 (Aβ1–42) peptide involved in Alzheimer's disease is known to
cause a dysregulation of intracellular Ca2+ homeostasis, its molecular mechanisms still …

Simple Summary Alzheimer's disease (AD) is a progressive neurodegenerative disorder
and represents the most common cause of dementia among elderly people. It is …

Intraneuronal amyloid β (Aβ) oligomer accumulation precedes the appearance of amyloid
plaques or neurofibrillary tangles and is neurotoxic. In Alzheimer's disease (AD)-affected …