Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Within the last decade, the application range of aptamers in biochemistry and medicine has
expanded rapidly. More than just a replacement for antibodies, these intrinsically structured …

Aptamers are small oligonucleotides that are capable of binding specifically to a target, with
impressive potential for analysis, diagnostics, and therapeutics applications. Aptamers are …

Portable devices capable of rapid disease detection and health monitoring are crucial to
decentralizing diagnostics from clinical laboratories to the patient point-of-need. Although …

This review is intended to guide the novice in aptamer research and development to
understand virtually all of the aptamer development options and currently available assay …

Aptamers are short nucleic acid sequences capable of specific, high-affinity molecular
binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential …

Single-stranded oligonucleotide aptamers have attracted great attention in the past decade
because of their diagnostic and therapeutic potential. These versatile, high affinity and …

Conspectus Although antibodies are a powerful tool for molecular biology and clinical
diagnostics, there are many emerging applications for which nucleic acid-based aptamers …

Aptamers are oligonucleotide receptors with great potential for sensing and therapeutic
applications. They are isolated from random libraries through an in vitro method termed …

Conspectus Affinity reagents that specifically bind to their target molecules are invaluable
tools in nearly every field of modern biomedicine. Nucleic acid-based aptamers offer many …