Secretion systems in Gram-negative bacteria: structural and mechanistic insights
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …
virulence factors across the bacterial cell envelope. In recent years, considerable progress …
Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells
One of the most exciting developments in the field of bacterial pathogenesis in recent years
is the discovery that many pathogens utilize complex nanomachines to deliver bacterially …
is the discovery that many pathogens utilize complex nanomachines to deliver bacterially …
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
Inflammasomes are large cytoplasmic complexes that sense microbial infections/danger
molecules and induce caspase-1 activation-dependent cytokine production and …
molecules and induce caspase-1 activation-dependent cytokine production and …
Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant-and animal-pathogenic bacteria
D Büttner - Microbiology and Molecular Biology Reviews, 2012 - Am Soc Microbiol
Flagellar and translocation-associated type III secretion (T3S) systems are present in most
Gram-negative plant-and animal-pathogenic bacteria and are often essential for bacterial …
Gram-negative plant-and animal-pathogenic bacteria and are often essential for bacterial …
Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
Inflammasome mediated by central nucleotide-binding and oligomerization domain (NOD)-
like receptor (NLR) protein is critical for defense against bacterial infection. Here we show …
like receptor (NLR) protein is critical for defense against bacterial infection. Here we show …
Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells
Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
Atomic model of the type III secretion system needle
Pathogenic bacteria using a type III secretion system (T3SS), to manipulate host cells cause
many different infections including Shigella dysentery, typhoid fever, enterohaemorrhagic …
many different infections including Shigella dysentery, typhoid fever, enterohaemorrhagic …
Assembly of the bacterial type III secretion machinery
Many bacteria that live in contact with eukaryotic hosts, whether as symbionts or as
pathogens, have evolved mechanisms that manipulate host cell behaviour to their benefit …
pathogens, have evolved mechanisms that manipulate host cell behaviour to their benefit …
[HTML][HTML] Assembly and structure of the T3SS
BJ Burkinshaw, NCJ Strynadka - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Abstract The Type III Secretion System (T3SS) is a multi-mega Dalton apparatus assembled
from more than twenty components and is found in many species of animal and plant …
from more than twenty components and is found in many species of animal and plant …
The structure and function of type III secretion systems
Type III secretion systems (T3SSs) afford Gram‐negative bacteria an intimate means of
altering the biology of their eukaryotic hosts—the direct delivery of effector proteins from the …
altering the biology of their eukaryotic hosts—the direct delivery of effector proteins from the …