Imaging techniques in Alzheimer's disease: a review of applications in early diagnosis and longitudinal monitoring

WM van Oostveen, ECM de Lange - International journal of molecular …, 2021 - mdpi.com
Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Magnetic resonance imaging in Alzheimer's disease and mild cognitive impairment

A Chandra, G Dervenoulas, M Politis… - Journal of …, 2019 - Springer
Research utilizing magnetic resonance imaging (MRI) has been crucial to the understanding
of the neuropathological mechanisms behind and clinical identification of Alzheimer's …

Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention

YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …

Multipronged diagnostic and therapeutic strategies for Alzheimer's disease

M Ramesh, T Govindaraju - Chemical science, 2022 - pubs.rsc.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major
contributor to dementia cases worldwide. AD is clinically characterized by learning, memory …

Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review

F Herold, A Törpel, L Schega, NG Müller - European Review of Aging and …, 2019 - Springer
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

Resting state abnormalities of the default mode network in mild cognitive impairment: a systematic review and meta-analysis

LT Eyler, JA Elman, SN Hatton… - Journal of …, 2019 - journals.sagepub.com
Background: Large-scale brain networks such as the default mode network (DMN) are often
disrupted in Alzheimer's disease (AD). Numerous studies have examined DMN functional …

Detecting early cognitive decline in Alzheimer's disease with brain synaptic structural and functional evaluation

S Ribarič - Biomedicines, 2023 - mdpi.com
Early cognitive decline in patients with Alzheimer's (AD) is associated with quantifiable
structural and functional connectivity changes in the brain. AD dysregulation of Aβ and tau …

[HTML][HTML] Biomarkers of Alzheimer's disease: Past, present and future clinical use

JE Georgakas, MD Howe, LI Thompson… - Biomarkers in …, 2023 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disease and the leading
cause of dementia worldwide. AD is associated with several neuropathologic changes …

Quantitation of in vivo brain glutathione conformers in cingulate cortex among age‐matched control, MCI, and AD patients using MEGA‐PRESS

D Shukla, PK Mandal, M Tripathi… - Human brain …, 2020 - Wiley Online Library
Oxidative stress (OS) plays an important role in Alzheimer's disease (AD) and glutathione
(GSH) mitigates this effect by maintaining redox‐imbalance and free‐radical neutralization …

Multi-Modal Diagnosis of Alzheimer's Disease using Interpretable Graph Convolutional Networks

H Zhou, L He, BY Chen, L Shen… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
The interconnection between brain regions in neurological disease encodes vital
information for the advancement of biomarkers and diagnostics. Although graph …