Red blood cells: chasing interactions

V Pretini, MH Koenen, L Kaestner, MHAM Fens… - Frontiers in …, 2019 - frontiersin.org
Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

Patrolling the vascular borders: platelets in immunity to infection and cancer

F Gaertner, S Massberg - Nature Reviews Immunology, 2019 - nature.com
Platelets are small anucleate cellular fragments that are released by megakaryocytes and
safeguard vascular integrity through a process termed 'haemostasis'. However, platelets …

Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease

S Cai, H Li, F Zheng, F Kong, M Dao… - Proceedings of the …, 2021 - National Acad Sciences
Understanding the mechanics of blood flow is necessary for develo** insights into
mechanisms of physiology and vascular diseases in microcirculation. Given the limitations of …

Near-infrared light–triggered platelet arsenal for combined photothermal-immunotherapy against cancer

Y Lv, F Li, S Wang, G Lu, W Bao, Y Wang, Z Tian… - Science …, 2021 - science.org
To address long-standing issues with tumor penetration and targeting among cancer
therapeutics, we developed an anticancer platelet-based biomimetic formulation (N+ R …

Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood

A Yazdani, Y Deng, H Li, E Javadi… - Journal of the …, 2021 - royalsocietypublishing.org
Normal haemostasis is an important physiological mechanism that prevents excessive
bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads …

Blood viscosity in subjects with type 2 diabetes mellitus: roles of hyperglycemia and elevated plasma fibrinogen

J Sun, K Han, M Xu, L Li, J Qian, L Li, X Li - Frontiers in Physiology, 2022 - frontiersin.org
The viscosity of blood is an indicator in the understanding and treatment of disease. An
elevated blood viscosity has been demonstrated in patients with Type 2 Diabetes Mellitus …

The flow of anisotropic nanoparticles in solution and in blood

JT Lovegrove, B Kent, S Förster, CJ Garvey… - …, 2023 - Wiley Online Library
The alignment of anisotropic nanoparticles in flow has been used for a range of applications
such as the preparation of strong fibres and the assembly of in‐plane aligned 1D …

Engineered platelets: advocates for tumor immunotherapy

Y Wang, Z Li, F Mo, Z Gu, Q Hu - Nano Today, 2021 - Elsevier
Platelets are crucial components in the blood circulation mainly responsible for hemostasis,
and they are also widely involved in dynamic physiological activities including inflammation …

Quantifying fibrinogen-dependent aggregation of red blood cells in type 2 diabetes mellitus

Y Deng, DP Papageorgiou, X Li, N Perakakis… - Biophysical journal, 2020 - cell.com
Fibrinogen is regarded as the main glycoprotein in the aggregation of red blood cells
(RBCs), a normally occurring phenomenon that has a major impact on blood rheology and …

Multiphysics and multiscale modeling of microthrombosis in COVID-19

H Li, Y Deng, Z Li, A Dorken Gallastegi… - PLOS Computational …, 2022 - journals.plos.org
Emerging clinical evidence suggests that thrombosis in the microvasculature of patients with
Coronavirus disease 2019 (COVID-19) plays an essential role in dictating the disease …