Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell...

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Recent developments in olfactory neuroblastoma research

A Ghanem, JB Finlay, DW Jang… - Current Opinion in …, 2025 - journals.lww.com
These findings have profound implications on clinical practice. Improved diagnostic
accuracy through advanced imaging and genomic profiling in addition to identifying specific …
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[HTML] modernpathology.org

Analysis of ASCL1/NEUROD1/POU2F3/YAP1 Yields Novel Insights for the Diagnosis of Olfactory Neuroblastoma and Identifies Sinonasal Tuft Cell–Like Carcinoma

CA Febres-Aldana, MM Elsayad, M Saliba, U Bhanot… - Modern Pathology, 2025 - Elsevier
The diagnosis and treatment of sinonasal small round epithelial/neuroepithelial
malignancies depend on the expression of conventional neuroendocrine markers (NEMs) …
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[HTML] mdpi.com

[HTML][HTML] Characterization of Somatostatin Receptor 2 Gene Expression and Immune Landscape in Sinonasal Malignancies

E Xue, D Bracken-Clarke, H Krause, T Adeyelu… - Cancers, 2024 - mdpi.com
Olfactory neuroblastoma (ONB), sinonasal undifferentiated carcinoma (SNUC), and
sinonasal neuroendocrine carcinoma (SNEC) are rare malignancies arising from the …
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[PDF] biorxiv.org

Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer

AS Ireland, SB Hawgood, DA **e, MW Barbier… - bioRxiv, 2024 - biorxiv.org
Neuroendocrine and tuft cells are rare, chemosensory epithelial lineages defined by
expression of ASCL1 and POU2F3 transcription factors, respectively. Neuroendocrine …
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[HTML] oaepublish.com

[HTML][HTML] Olfactory neuroblastoma

S Okafor, S AlShammari, V Helou, M Mitchell… - Mini-invasive …, 2024 - oaepublish.com
Originating from the olfactory neuroepithelium, olfactory neuroblastoma is a rare malignant
tumor of the nasal cavity that typically affects adults between the ages of 35 and 70. Clinical …
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