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The 2019 mathematical oncology roadmap
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Stimulating intrinsic motivation in millennial students: A new generation, a new approach
JD Chaudhuri - Anatomical sciences education, 2020 - Wiley Online Library
There has been a fundamental change in health care pedagogy to address the demands
and challenges posed by the present generation of millennial students. There is also a …
and challenges posed by the present generation of millennial students. There is also a …
Sharing biological data: why, when, and how
Sharing data has a crucial role in the advancement of biological science. The use of different
types of data within and between scientific fields complicates establishing a single standard …
types of data within and between scientific fields complicates establishing a single standard …
Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology
Computational models are often employed in systems biology to study the dynamic
behaviours of complex systems. With the rise in the number of computational models, finding …
behaviours of complex systems. With the rise in the number of computational models, finding …
High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow
Background Cancer is a complex, multiscale dynamical system, with interactions between
tumor cells and non-cancerous host systems. Therapies act on this combined cancer-host …
tumor cells and non-cancerous host systems. Therapies act on this combined cancer-host …
Creating a structured adverse outcome pathway knowledgebase via ontology-based annotations
C Ives, I Campia, RL Wang, C Wittwehr… - Applied in vitro …, 2017 - liebertpub.com
Abstract The Adverse Outcome Pathway (AOP) framework is increasingly used to integrate
data based on traditional and emerging toxicity testing paradigms. As the number of AOP …
data based on traditional and emerging toxicity testing paradigms. As the number of AOP …
Agent-based modeling of cancer stem cell driven solid tumor growth
Computational modeling of tumor growth has become an invaluable tool to simulate
complex cell–cell interactions and emerging population-level dynamics. Agent-based …
complex cell–cell interactions and emerging population-level dynamics. Agent-based …
Computational modeling of development by epithelia, mesenchyme and their interactions: a unified model
Motivation: The transformation of the embryo during development requires complex gene
networks, cell signaling and gene-regulated cell behaviors (division, adhesion, polarization …
networks, cell signaling and gene-regulated cell behaviors (division, adhesion, polarization …
Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
Cells are fundamental units of life, constantly interacting and evolving as dynamical systems.
While recent spatial multi-omics can quantitate individual cells' characteristics and …
While recent spatial multi-omics can quantitate individual cells' characteristics and …
[PDF][PDF] Key challenges facing data-driven multicellular systems biology
P Macklin - Gigascience, 2019 - academic.oup.com
Increasingly sophisticated experiments, coupled with large-scale computational models,
have the potential to systematically test biological hypotheses to drive our understanding of …
have the potential to systematically test biological hypotheses to drive our understanding of …