Strategies for non-viral vectors targeting organs beyond the liver

J Kim, Y Eygeris, RC Ryals, A Jozić, G Sahay - Nature nanotechnology, 2024 - nature.com
In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …

Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

[HTML][HTML] Magnetic nanoparticles in biomedical applications: A review

EM Materón, CM Miyazaki, O Carr, N Joshi… - Applied Surface Science …, 2021 - Elsevier
Biomedical applications with emphasis on the design of smart materials, specifically
magnetic nanoparticles (MNPs) are considered to have technological benefits because they …

Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Mechanism insights and therapeutic intervention of tumor metastasis: latest developments and perspectives

X Shi, X Wang, W Yao, D Shi, X Shao, Z Lu… - Signal transduction and …, 2024 - nature.com
Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

[HTML][HTML] Development of pharmaceutical nanomedicines: from the bench to the market

AA Halwani - Pharmaceutics, 2022 - mdpi.com
Nanotechnology plays a significant role in the field of medicine and in drug delivery, mainly
due to the major limitations affecting the conventional pharmaceutical agents, and older …

Lighting up metastasis process before formation of secondary tumor by phosphorescence imaging

K Chang, L **ao, Y Fan, J Gu, Y Wang, J Yang… - Science …, 2023 - science.org
Metastasis is the leading cause of cancer-related deaths; until now, the detection of tumor
metastasis is mainly located at the period that secondary tumors have been formed, which …

A review on graphene-based nanocomposites for electrochemical and fluorescent biosensors

SK Krishnan, E Singh, P Singh, M Meyyappan… - RSC …, 2019 - pubs.rsc.org
Biosensors with high sensitivity, selectivity and a low limit of detection, reaching
nano/picomolar concentrations of biomolecules, are important to the medical sciences and …

[HTML][HTML] Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications

N Singh, J Kim, J Kim, K Lee, Z Zunbul, I Lee, E Kim… - Bioactive materials, 2023 - Elsevier
Nanomedicines for drug delivery and imaging-guided cancer therapy is a rapidly growing
research area. The unique properties of nanomedicines have a massive potential in solving …

Survey of clinical translation of cancer nanomedicines—lessons learned from successes and failures

H He, L Liu, EE Morin, M Liu… - Accounts of chemical …, 2019 - ACS Publications
Conspectus In 1995, the year the first cancer nanomedicine, Doxil, was approved by the
Food and Drug Administration (FDA), only 23 manuscripts appeared in a PubMed search for …