Visible-light-mediated modification and manipulation of biomacromolecules
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …
have become crucial tools in chemical biology. They are extensively used not only to …
Interrogating biological systems using visible-light-powered catalysis
Light-powered catalysis has found broad utility as a chemical transformation strategy, with
widespread impact on energy, environment, drug discovery and human health. A noteworthy …
widespread impact on energy, environment, drug discovery and human health. A noteworthy …
Catalytic photooxygenation degrades brain Aβ in vivo
Protein degradation induced by small molecules by recruiting endogenous protein
degradation systems, such as ubiquitin-proteasome systems, to disease-related proteins is …
degradation systems, such as ubiquitin-proteasome systems, to disease-related proteins is …
Membrane intercalation-enhanced photodynamic inactivation of bacteria by a metallacycle and TAT-decorated virus coat protein
S Gao, X Yan, G **e, M Zhu, X Ju… - Proceedings of the …, 2019 - National Acad Sciences
Antibiotic resistance has become one of the major threats to global health. Photodynamic
inactivation (PDI) develops little antibiotic resistance; thus, it becomes a promising strategy …
inactivation (PDI) develops little antibiotic resistance; thus, it becomes a promising strategy …
A Gd-doped polydopamine (PDA)-based theranostic nanoplatform as a strong MR/PA dual-modal imaging agent for PTT/PDT synergistic therapy
Y Pu, Y Zhu, Z Qiao, N **n, S Chen, J Sun… - Journal of Materials …, 2021 - pubs.rsc.org
Based on widely used photoacoustic imaging (PAI) and photothermal properties of
polydopamine (PDA), a multifunctional Gd–PDA-Ce6@ Gd-MOF (GPCG) nanosystem with a …
polydopamine (PDA), a multifunctional Gd–PDA-Ce6@ Gd-MOF (GPCG) nanosystem with a …
Manganese‐doped green tea‐derived carbon quantum dots as a targeted dual imaging and photodynamic therapy platform
In this work, manganese‐doped carbon quantum dots (Mn‐CQDs) have been synthesized
through a one‐pot hydrothermal method by using waste green tea. The Mn2+ dopants were …
through a one‐pot hydrothermal method by using waste green tea. The Mn2+ dopants were …
Treatment of Alzheimer's disease with small-molecule photosensitizers
Y Jiang, Z Zeng, J Yao, Y Guan, P Jia, X Zhao… - Chinese Chemical …, 2023 - Elsevier
Alzheimer's disease is a neurodegenerative disease that signals for excess β-amyloid (Aβ)
aggregation. Although people have made great attempts to control the aggregation of Aβ, no …
aggregation. Although people have made great attempts to control the aggregation of Aβ, no …
Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins
Catalytic photo-oxygenation of tau amyloid is a potential therapeutic approach to
tauopathies, including Alzheimer disease (AD). However, tau is a complex target containing …
tauopathies, including Alzheimer disease (AD). However, tau is a complex target containing …
Noninvasive Treatment of Alzheimer's Disease with Scintillating Nanotubes
Effective and accessible treatments for Alzheimer's disease (AD) are urgently needed.
Soluble Aβ oligomers are identified as neurotoxic species in AD and targeted in antibody …
Soluble Aβ oligomers are identified as neurotoxic species in AD and targeted in antibody …
[HTML][HTML] Mercury and Alzheimer's disease: Hg (II) ions display specific binding to the amyloid-β peptide and hinder its fibrillization
Brains and blood of Alzheimer's disease (AD) patients have shown elevated mercury
concentrations, but potential involvement of mercury exposure in AD pathogenesis has not …
concentrations, but potential involvement of mercury exposure in AD pathogenesis has not …