Disconnecting multicellular networks in brain tumours

V Venkataramani, M Schneider, FA Giordano… - Nature Reviews …, 2022 - nature.com
Cancer cells can organize and communicate in functional networks. Similarly to other
networks in biology and sociology, these can be highly relevant for growth and resilience. In …

Role of the microenvironment in glioma pathogenesis

MA Jayaram, JJ Phillips - Annual Review of Pathology …, 2024 - annualreviews.org
Gliomas are a diverse group of primary central nervous system tumors that affect both
children and adults. Recent studies have revealed a dynamic cross talk that occurs between …

Glioblastoma remodelling of human neural circuits decreases survival

S Krishna, A Choudhury, MB Keough, K Seo, L Ni… - Nature, 2023 - nature.com
Gliomas synaptically integrate into neural circuits,. Previous research has demonstrated
bidirectional interactions between neurons and glioma cells, with neuronal activity driving …

Modified Neuropixels probes for recording human neurophysiology in the operating room

B Coughlin, W Muñoz, Y Kfir, MJ Young, D Meszéna… - Nature …, 2023 - nature.com
Neuropixels are silicon-based electrophysiology-recording probes with high channel count
and recording-site density. These probes offer a turnkey platform for measuring neural …

Regional healthy brain activity, glioma occurrence and symptomatology

T Numan, LC Breedt, BAPC Maciel, SD Kulik, J Derks… - Brain, 2022 - academic.oup.com
It is unclear why exactly gliomas show preferential occurrence in certain brain areas.
Increased spiking activity around gliomas leads to faster tumour growth in animal models …

[HTML][HTML] The impact of etiology in lesion-symptom map**–a direct comparison between tumor and stroke

EE Van Grinsven, AR Smits, E Van Kessel… - NeuroImage: Clinical, 2023 - Elsevier
Introduction Lesion-symptom map** is a key tool in understanding the relationship
between brain structures and behavior. However, the behavioral consequences of lesions …

Neurons as stromal drivers of nervous system cancer formation and progression

C Anastasaki, Y Gao, DH Gutmann - Developmental cell, 2023 - cell.com
Similar to their pivotal roles in nervous system development, neurons have emerged as
critical regulators of cancer initiation, maintenance, and progression. Focusing on nervous …

Brain network map** and glioma pathophysiology

AS Mandal, S Brem, J Suckling - Brain Communications, 2023 - academic.oup.com
Adult diffuse gliomas are among the most difficult brain disorders to treat in part due to a lack
of clarity regarding the anatomical origins and mechanisms of migration of the tumours …

Involvement of white matter language tracts in glioma: Clinical implications, operative management, and functional recovery after injury

AA Aabedi, JS Young, EF Chang, MS Berger… - Frontiers in …, 2022 - frontiersin.org
To achieve optimal survival and quality of life outcomes in patients with glioma, the extent of
tumor resection must be maximized without causing injury to eloquent structures …

An electroencephalogram microdisplay to visualize neuronal activity on the brain surface

Y Tchoe, T Wu, HS U, DM Roth, D Kim, J Lee… - Science translational …, 2024 - science.org
Functional map** during brain surgery is applied to define brain areas that control critical
functions and cannot be removed. Currently, these procedures rely on verbal interactions …