To execute their many vital functions, cell membranes are highly organized. Here, we review
how membrane structure shapes signal transduction across membranes. Recent …

When two monolayers of a non-lamellar lipid are brought together to form a planar bilayer
membrane, the resulting structure is under elastic stress. This stress changes the …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

The membrane-lytic peptide melittin has previously been shown to form pores in lipid
bilayers that have been described in terms of two different structural models. In the" barrel …

A simple extension of the EEF1 energy function to heterogeneous membrane‐aqueous
media is proposed. The extension consists of (a) development of solvation parameters for a …

The free energy difference associated with the transfer of a single cholesterol molecule from
the aqueous phase into a lipid bilayer depends on its final location, namely on its insertion …

Alamethicin is an antimicrobial peptide that forms stable channels with well-defined
conductance levels. We have used extended molecular dynamics simulations of alamethicin …

Sum frequency generation (SFG) vibrational spectroscopy has been demonstrated to be a
powerful technique to study the molecular structures of surfaces and interfaces in different …

Although the antimicrobial, fungal peptide alamethicin has been extensively studied, the
conformation of the peptide and the interaction with lipid bilayers as well as the mechanism …

Ion channels play crucial roles in transport and regulatory functions of living cells.
Understanding the gating mechanisms of these channels is important to understanding and …