The epidermal growth factor receptor (EGFR) belongs to the ERBB family of tyrosine kinase
receptors. EGFR signaling cascade is a key regulator in cell proliferation, differentiation …

How bacteria grow and divide while retaining a defined shape is a fundamental question in
microbiology, but technological advances are now driving a new understanding of how the …

A system-wide understanding of cellular function requires knowledge of all functional
interactions between the expressed proteins. The STRING database aims to collect and …

The many functional partnerships and interactions that occur between proteins are at the
core of cellular processing and their systematic characterization helps to provide context in …

Melanoma treatment is being revolutionized by the development of effective
immunotherapeutic approaches,. These strategies include blockade of immune-inhibitory …

Complete knowledge of all direct and indirect interactions between proteins in a given cell
would represent an important milestone towards a comprehensive description of cellular …

Our knowledge of species and functional composition of the human gut microbiome is
rapidly increasing, but it is still based on very few cohorts and little is known about variation …

Abstract GeneMANIA (http://www. genemania. org) is a flexible, user-friendly web interface
for generating hypotheses about gene function, analyzing gene lists and prioritizing genes …

An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …

Lysine acetylation is a reversible posttranslational modification of proteins and plays a key
role in regulating gene expression. Technological limitations have so far prevented a global …