Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

Microorganisms produce a wealth of structurally diverse specialized metabolites with a
remarkable range of biological activities and a wide variety of applications in medicine and …

Covering: 2006 to 2016 The computational mining of genomes has become an important
part in the discovery of novel natural products as drug leads. Thousands of bacterial …

Isoprenoid biosynthesis is essential for all living organisms, and isoprenoids are also of
industrial and agricultural interest. All isoprenoids are derived from prenyl diphosphate …

Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …

The rich diversity of secondary metabolites produced by soil bacteria has been appreciated
for over a century, and advances in chemical analysis and genome sequencing continue to …

Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Bacillus subtilis is widely underappreciated for its inherent biosynthetic potential. This report
comprehensively summarizes the known bioactive secondary metabolites from B. subtilis …

Genomic data often highlights an inconsistency between the number of gene clusters
identified using bioinformatic approaches as potentially producing secondary metabolites …