Mismatch repair stabilizes the cellular genome by correcting DNA replication errors and by
blocking recombination events between divergent DNA sequences. The reaction …

Nucleases cleave the phosphodiester bonds of nucleic acids and may be endo or exo,
DNase or RNase, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes. In …

A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing
endonucleases and related genes and gene products. It provides explicit categories for the …

Our understanding of the evolution of DNA restriction and modification systems, the control
of the expression of the structural genes for the enzymes, and the importance of DNA …

The construction of a variety of strains deficient in the methylation of adenine and cytosine
residues in DNA by the methyltransferases (MTases) Dam and Dcm has allowed the study of …

DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA
replication errors. The fundamental mechanisms and proteins involved in the early reactions …

The DNA adenine methyltransferase (Dam methylase) of Gammaproteobacteria and the cell
cycle-regulated methyltransferase (CcrM) methylase of Alphaproteobacteria catalyze an …

A list of currently identified gene products of Escherichia coli is given, together with a
bibliography that provides pointers to the literature on each gene product. A scheme to …

Methylcytosine in DNA is genetically unstable. Methylated CpG (mCpG) sequences
frequently undergo mutation resulting in a general depletion of this dinucleotide sequence in …

8-Oxoguanine nucleotide can pair with cytosine and adenine nucleotides at almost equal
efficiencies. Once 8-oxodGTP is formed in the cellular nucleotide pool, this mutagenic …