A review on CRISPR/Cas: a versatile tool for cancer screening, diagnosis, and clinic treatment
X Yang, B Zhang - Functional & Integrative Genomics, 2023 - Springer
Cancer is one of the leading causes of death worldwide and it has the trend of increase
incidence. However, in the past decades, as quickly developed new technologies and …
incidence. However, in the past decades, as quickly developed new technologies and …
MicroRNAs in tumor cell metabolism: roles and therapeutic opportunities
Dysregulated metabolism is a common feature of cancer cells and is considered a hallmark
of cancer. Altered tumor-metabolism confers an adaptive advantage to cancer cells to fulfill …
of cancer. Altered tumor-metabolism confers an adaptive advantage to cancer cells to fulfill …
Hyaluronic acid‐decorated liposomal nanoparticles for targeted delivery of 5‐fluorouracil into HT‐29 colorectal cancer cells
The use of liposomes as drug carriers improves the therapeutic efficacy of anticancer drugs,
while at the same time reducing side effects. Hyaluronic acid (HA) is recognized by the …
while at the same time reducing side effects. Hyaluronic acid (HA) is recognized by the …
Controlled self-assembly of a close-packed gold octahedra array for SERS sensing exosomal microRNAs
T Kang, J Zhu, X Luo, W Jia, P Wu, C Cai - Analytical Chemistry, 2021 - ACS Publications
MicroRNAs (miRNAs) in exosomes can be transferred from parental cells to recipient cells
by trafficking exosomes, and they are effective in regulating the gene expression of the …
by trafficking exosomes, and they are effective in regulating the gene expression of the …
A novel view on an old drug, 5-fluorouracil: an unexpected RNA modifier with intriguing impact on cancer cell fate
M Chalabi-Dchar, T Fenouil, C Machon, A Vincent… - NAR …, 2021 - academic.oup.com
Fluorouracil (5-FU) is a chemotherapeutic drug widely used to treat patients with solid
tumours, such as colorectal and pancreatic cancers. Colorectal cancer (CRC) is the second …
tumours, such as colorectal and pancreatic cancers. Colorectal cancer (CRC) is the second …
miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4
Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths
worldwide. The role of microRNAs (miRNAs/miRs) as small (19–25 nucleotides in length) …
worldwide. The role of microRNAs (miRNAs/miRs) as small (19–25 nucleotides in length) …
MicroRNA pharmacogenomics: post-transcriptional regulation of drug response
JL Rukov, N Shomron - Trends in molecular medicine, 2011 - cell.com
The field of pharmacogenomics aims to predict which drugs will be most effective and safe
for a particular individual based on their genome sequence or expression profile, thereby …
for a particular individual based on their genome sequence or expression profile, thereby …
Metabolism-related microRNAs in maternal breast milk are influenced by premature delivery
MC Carney, A Tarasiuk, SL DiAngelo, P Silveyra… - Pediatric …, 2017 - nature.com
Background Maternal breast milk (MBM) is enriched in microRNAs, factors that regulate
protein translation throughout the human body. MBM from mothers of term and preterm …
protein translation throughout the human body. MBM from mothers of term and preterm …
Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line
SE Yazdi Rouholamini, S Moghassemi… - Artificial cells …, 2018 - Taylor & Francis
Silibinin is a natural flavonoid with a strong antioxidant property and weak cytotoxic activity.
It has demonstrated anti-tumoural activity against many types of malignancies; however, due …
It has demonstrated anti-tumoural activity against many types of malignancies; however, due …
Celf family proteins in cancer: Highlights on the rna-binding protein/noncoding rna regulatory axis
M Nasiri-Aghdam, TC Garcia-Garduño… - International journal of …, 2021 - mdpi.com
Post-transcriptional modifications to coding and non-coding RNAs are unquestionably a
pivotal way in which human mRNA and protein diversity can influence the different phases …
pivotal way in which human mRNA and protein diversity can influence the different phases …