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Biomedical applications of nanomaterials in the advancement of nucleic acid therapy: mechanistic challenges, delivery strategies, and therapeutic applications
In the past few decades, substantial advancement has been made in nucleic acid (NA)-
based therapies. Promising treatments include mRNA, siRNA, miRNA, and anti-sense DNA …
based therapies. Promising treatments include mRNA, siRNA, miRNA, and anti-sense DNA …
Exosome-based macromolecular neurotherapeutic drug delivery approaches in overcoming the blood-brain barrier for treating brain disorders
Delivering drugs to the brain is a complex challenge in medical research, particularly for
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …
[HTML][HTML] Understanding the prospective of nano-formulations towards the treatment of psoriasis
Psoriasis is a consistently recurring, inflammatory, autoimmune disorder of the skin, affecting
about 2–5% of the world population. Abundant therapeutic agents are accessible for the …
about 2–5% of the world population. Abundant therapeutic agents are accessible for the …
Preclinical study models of psoriasis: State-of-the-art techniques for testing pharmaceutical products in animal and nonanimal models
Local and systemic treatments exist for psoriasis, but none can do more than control its
symptoms because of its numerous unknown mechanisms. The lack of validated testing …
symptoms because of its numerous unknown mechanisms. The lack of validated testing …
Statistically optimized calcipotriol fused nanostructured lipid carriers for effectual topical treatment of psoriasis
Present work focuses on the development and optimization (Box-Behnken design) of
calcipotriol (CP) loaded nanostructured lipid carrier (NLC) enriched nanogel for topical …
calcipotriol (CP) loaded nanostructured lipid carrier (NLC) enriched nanogel for topical …
Nanotechnology in diabetes management: Revolutionizing treatment and diagnostics
K Yadav - Journal of Molecular Liquids, 2024 - Elsevier
The global health landscape is witnessing a paradigm shift as diabetes emerges as a
formidable challenge to conventional medical interventions. This metabolic disorder …
formidable challenge to conventional medical interventions. This metabolic disorder …
Novel archetype in psoriasis management bridging molecular dynamics in exploring novel therapies
K Yadav, D Singh, MR Singh - European Journal of Pharmacology, 2021 - Elsevier
Psoriasis is an autoimmune chronic inflammatory condition of skin affecting 125 million
populaces around the globe. It is implicated as a result of multifaceted phenomena involving …
populaces around the globe. It is implicated as a result of multifaceted phenomena involving …
Unleashing the potential of natural protein based nanoparticles for the delivery of therapeutic nucleic Acid: A comprehensive review
Nucleic acid-based therapeutics represent a revolutionary approach in treating genetic
disorders, offering unprecedented potential for addressing pathologies at their molecular …
disorders, offering unprecedented potential for addressing pathologies at their molecular …
Development and characterization of corticosteroid loaded lipid carrier system for psoriasis
K Yadav, D Singh, MR Singh - Research Journal of Pharmacy …, 2021 - indianjournals.com
Psoriasis is a highly complex autoimmune disease of skin with keratinocytes that
differentiate abnormally. Because of the inaccessibility of the adequate delivery system, a …
differentiate abnormally. Because of the inaccessibility of the adequate delivery system, a …
Perspectives of lipid-based drug carrier systems for transdermal delivery
Transdermal delivery serves as non-invasive and effortless terminable means for systemic
as well as topical drug delivery and finds itself as an option to conventional delivery route …
as well as topical drug delivery and finds itself as an option to conventional delivery route …