Antipsychotic drugs: from receptor-binding profiles to metabolic side effects
Background: Antipsychotic-induced metabolic side effects are major concerns in
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
Activity based anorexia as an animal model for anorexia nervosa–a systematic review
MA Schalla, A Stengel - Frontiers in nutrition, 2019 - frontiersin.org
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons.
However, the knowledge about its underlying pathophysiology is limited. To address the …
However, the knowledge about its underlying pathophysiology is limited. To address the …
A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice
Midbrain dopamine (DA) and serotonin (5-HT) neurons regulate motivated behaviors,
including feeding, but less is known about how these circuits may interact. In this study, we …
including feeding, but less is known about how these circuits may interact. In this study, we …
Animal models for anorexia nervosa—a systematic review
S Scharner, A Stengel - Frontiers in human neuroscience, 2021 - frontiersin.org
Anorexia nervosa is an eating disorder characterized by intense fear of gaining weight and a
distorted body image which usually leads to low caloric intake and hyperactivity. The …
distorted body image which usually leads to low caloric intake and hyperactivity. The …
Understanding the effects of antipsychotics on appetite control
Antipsychotic drugs (APDs) represent a cornerstone in the treatment of schizophrenia and
other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so …
other psychoses. The effectiveness of the first generation (typical) APDs are hampered by so …
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
[HTML][HTML] Associations between aerobic exercise and dopamine-related reward-processing: Informing a model of human exercise engagement
Endurance or aerobic exercise has many physical and mental health benefits, but less is
known about the specific impact that cardiovascular activity may have on dopamine …
known about the specific impact that cardiovascular activity may have on dopamine …
The role of the human hypothalamus in food intake networks: An MRI perspective
C Roger, A Lasbleiz, M Guye, A Dutour, B Gaborit… - Frontiers in …, 2022 - frontiersin.org
Hypothalamus (HT), this small structure often perceived through the prism of neuroimaging
as morphologically and functionally homogeneous, plays a key role in the primitive act of …
as morphologically and functionally homogeneous, plays a key role in the primitive act of …
Suppression of corticostriatal circuit activity improves cognitive flexibility and prevents body weight loss in activity-based anorexia in rats
Background The ability to adapt behavior to changing environmental circumstances, or
cognitive flexibility, is impaired in multiple psychiatric conditions, including anorexia nervosa …
cognitive flexibility, is impaired in multiple psychiatric conditions, including anorexia nervosa …
Activity-based anorexia animal model: a review of the main neurobiological findings
Background The genesis of anorexia nervosa (AN), a severe eating disorder with a
pervasive effect on many brain functions such as attention, emotions, reward processing …
pervasive effect on many brain functions such as attention, emotions, reward processing …