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A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy
Increasing evidence suggests that the gut microbiome may modulate the efficacy of cancer
immunotherapy. In a B cell lymphoma patient cohort from five centers in Germany and the …
immunotherapy. In a B cell lymphoma patient cohort from five centers in Germany and the …
Antibiotics: from mechanism of action to resistance and beyond
Antibiotics are the super drugs that have revolutionized modern medicine by curing many
infectious diseases caused by various microbes. They efficiently inhibit the growth and …
infectious diseases caused by various microbes. They efficiently inhibit the growth and …
[HTML][HTML] Biofilm Production in Intensive Care Units: Challenges and Implications
The prevalence of infections amongst intensive care unit (ICU) patients is inevitably high,
and the ICU is considered the epicenter for the spread of multidrug-resistant bacteria …
and the ICU is considered the epicenter for the spread of multidrug-resistant bacteria …
Short-and long-term effects of different antibiotics on the gut microbiota and cytokines level in mice
J Wang, Q **ang, S Gu, Y Gu, M Yao… - Infection and Drug …, 2022 - Taylor & Francis
Background Antibiotics are the first line of treatment for infectious diseases. However, their
overuse can increase the spread of drug-resistant bacteria. The present study analyzed the …
overuse can increase the spread of drug-resistant bacteria. The present study analyzed the …
Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice
MK Joo, YJ Shin, DH Kim - Scientific Reports, 2023 - nature.com
Antibiotics are increasingly recognized as causing neuropsychiatric side effects including
depression and anxiety. Alterations in central serotonin and 5-HT receptor expression are …
depression and anxiety. Alterations in central serotonin and 5-HT receptor expression are …
Vagus nerve-dependent effects of fluoxetine on anxiety-and depression-like behaviors in mice
MK Joo, DH Kim - European journal of pharmacology, 2023 - Elsevier
The vagus nerve is a major pathway in the body that is responsible for regulating the activity
of the parasympathetic nervous system, which plays an important role in mood disorders …
of the parasympathetic nervous system, which plays an important role in mood disorders …
Moderate and transient impact of antibiotic use on the gut microbiota in a rural Vietnamese cohort
VTN Bich, NG Le, D Barnett, J Chan, N van Best… - Scientific Reports, 2022 - nature.com
The human gut microbiota has been shown to be significantly perturbed by antibiotic use,
while recovering to the pre-treatment state several weeks after short antibiotic exposure. The …
while recovering to the pre-treatment state several weeks after short antibiotic exposure. The …
Early reduction in gut microbiota diversity in critically ill patients is associated with mortality
Critical illness is associated with an altered gut microbiota, yet its association with poor
outcomes remains unclear. This study evaluates the early gut microbiota diversity changes …
outcomes remains unclear. This study evaluates the early gut microbiota diversity changes …
[PDF][PDF] Factor associated with in-hospital mortality among infective endocarditis patients
HH Chua, AYY Fong - J. Malays, 2023 - e-mjm.org
Introduction: Despite recent advancements in the diagnosis and management of infective
endocarditis (IE), it is associated with substantial morbidity and mortality. Our study objective …
endocarditis (IE), it is associated with substantial morbidity and mortality. Our study objective …
Recent Insights into the Evolving Role of the Gut Microbiome in Critical Care
Over the past decade, there has been an exponential increase in our understanding of
crucial roles played by the human microbiota (ie, complex community of bacteria, fungi, and …
crucial roles played by the human microbiota (ie, complex community of bacteria, fungi, and …