Safety of nanoparticles in medicine

J Wolfram, M Zhu, Y Yang, J Shen, E Gentile… - Current drug …, 2015 - ingentaconnect.com
Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …

[HTML][HTML] Harnessing nanoparticles for immunomodulation and vaccines

AC Gomes, M Mohsen, MF Bachmann - Vaccines, 2017 - mdpi.com
The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years
ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has …

Overcoming the crystallization and designability issues in the ultrastable zirconium phosphonate framework system

T Zheng, Z Yang, D Gui, Z Liu, X Wang, X Dai… - Nature …, 2017 - nature.com
Metal-organic frameworks (MOFs) based on zirconium phosphonates exhibit superior
chemical stability suitable for applications under harsh conditions. These compounds mostly …

The nano-plasma interface: Implications of the protein corona

J Wolfram, Y Yang, J Shen, A Moten, C Chen… - Colloids and Surfaces B …, 2014 - Elsevier
The interactions between nanoparticles and macromolecules in the blood plasma dictate the
biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of …

Protein corona mitigates the cytotoxicity of graphene oxide by reducing its physical interaction with cell membrane

G Duan, S Kang, X Tian, JA Garate, L Zhao, C Ge… - Nanoscale, 2015 - pubs.rsc.org
Many recent studies have shown that the way nanoparticles interact with cells and biological
molecules can vary greatly in the serum-containing or serum-free culture medium. However …

Computational biomaterials: computational simulations for biomedicine

X Dai, Y Chen - Advanced Materials, 2023 - Wiley Online Library
With the flourishing development of material simulation methods (quantum chemistry
methods, molecular dynamics, Monte Carlo, phase field, etc.), extensive adoption of …

Back to basics: exploiting the innate physico‐chemical characteristics of nanomaterials for biomedical applications

CY Tay, MI Setyawati, J **e, WJ Parak… - Advanced functional …, 2014 - Wiley Online Library
In nanomedicine design, emphasis is centered on the engineered impacts of the
nanomaterials (NMs). However, failure to understand the unintended effects of …

Opening lids: modulation of lipase immobilization by graphene oxides

M Mathesh, B Luan, TO Akanbi, JK Weber, J Liu… - ACS …, 2016 - ACS Publications
Lipases, which can be immobilized and reused for many reaction cycles, are important
enzymes with many industrial applications. A key challenge in lipase immobilization for …

[SÁCH][B] Engineered nanoparticles: structure, properties and mechanisms of toxicity

AK Singh - 2015 - books.google.com
Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an
indispensable introduction to engineered nanomaterials (ENM) and their potential adverse …

Graphene can wreak havoc with cell membranes

M Dallavalle, M Calvaresi, A Bottoni… - … applied materials & …, 2015 - ACS Publications
Molecular dynamics coarse grained to the level of hydrophobic and hydrophilic
interactions shows that small hydrophobic graphene sheets pierce through the …