The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Neutrophils, the most abundant white blood cells in humans, are critical for host defense
against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils …

Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced
mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of …

The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …

Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …

Neutrophil granulocytes form the first line of host defense against invading pathogens and
tissue injury. They are rapidly recruited from the blood to the affected sites, where they …

Comprising the majority of leukocytes in humans, neutrophils are the first immune cells to
respond to inflammatory or infectious etiologies and are crucial participants in the proper …

Sepsis is an infection-induced severe inflammatory disorder that leads to multiple organ
failure. Amongst organs affected, myocardial depression is believed to be a major …

Staphylococcus aureus is a leading cause of biofilm-associated prosthetic joint infection
(PJI), resulting in considerable disability and prolonged treatment. It is known that host …

Neutrophils are the most abundant innate immune cells. The pathogenic roles of neutrophils
are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic …