Radioembolization is an established treatment for chemoresistant and unresectable liver
cancers. Currently, treatment planning is often based on semi-empirical methods, which …

Primary liver tumours (ie hepatocellular carcinoma (HCC) or intrahepatic
cholangiocarcinoma (ICC)) are among the most frequent cancers worldwide. However, only …

OBJECTIVE. This article reviews recent developments in targeted radionuclide therapy
(TRT) approaches directed to malignant liver lesions, bone metastases, neuroendocrine …

Purpose A multidisciplinary expert panel convened to formulate state-of-the-art
recommendations for optimisation of selective internal radiation therapy (SIRT) with yttrium …

Purpose As an alternative to technetium-99m-macroaggregated albumin (99m Tc-MAA), a
scout dose of holmium-166 (166 Ho) microspheres can be used prior to 166 Ho …

Purpose To investigate hepatocellular carcinoma tumor dose-response characteristics
based on voxel-level absorbed doses (D) and biological effective doses (BED) using …

Trans-arterial radioembolization is currently performed using 90Y-loaded glass or resin
microspheres and also using 166Ho-loaded microspheres. The goal of this review is to …

Purpose To evaluate whether technetium-99 (99m Tc)-labeled macroaggregated albumin
(MAA) can predict subsequent yttrium-90 (90 Y) distribution and imaging response in …

Selective internal radiation therapy (SIRT) of hepatocellular carcinoma (HCC) has been
used for many years, usually without any specific dosimetry endpoint. Despite good clinical …

Abstract Background & Aims Efficacy of radioembolization is derived from radioinduced
damage, whereas tumour dosimetry is not considered as yet in prospective clinical trials …