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Brain-gut-microbiota axis in Alzheimer's disease
K Kowalski, A Mulak - Journal of neurogastroenterology and …, 2019 - pmc.ncbi.nlm.nih.gov
Disturbances along the brain-gut-microbiota axis may significantly contribute to the
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
Gram-negative bacteria and their lipopolysaccharides in Alzheimer's disease: pathologic roles and therapeutic implications
H Kim, S Kim, SJ Shin, YH Park, Y Nam, C Kim… - Translational …, 2021 - Springer
Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and
causes destructive and irreversible cognitive decline. Failures in the development of …
causes destructive and irreversible cognitive decline. Failures in the development of …
Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
SG Chen, V Stribinskis, MJ Rane, DR Demuth… - Scientific reports, 2016 - nature.com
Misfolded alpha-synuclein (AS) and other neurodegenerative disorder proteins display prion-
like transmission of protein aggregation. Factors responsible for the initiation of AS …
like transmission of protein aggregation. Factors responsible for the initiation of AS …
Mechanisms of molecular mimicry involving the microbiota in neurodegeneration
RP Friedland - Journal of Alzheimer's Disease, 2015 - content.iospress.com
The concept of molecular mimicry was established to explain commonalities of structure
which developed in response to evolutionary pressures. Most examples of molecular …
which developed in response to evolutionary pressures. Most examples of molecular …
Exploring pathological link between antimicrobial and amyloid peptides
Amyloid peptides (AMYs) and antimicrobial peptides (AMPs) are considered as the two
distinct families of peptides, characterized by their unique sequences, structures, biological …
distinct families of peptides, characterized by their unique sequences, structures, biological …
Curli biogenesis and function
MM Barnhart, MR Chapman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Curli are the major proteinaceous component of a complex extracellular matrix produced by
many Enterobacteriaceae. Curli were first discovered in the late 1980s on Escherichia coli …
many Enterobacteriaceae. Curli were first discovered in the late 1980s on Escherichia coli …
Functional amyloid–from bacteria to humans
Amyloid–a fibrillar, cross β-sheet quaternary structure–was first discovered in the context of
human disease and tissue damage, and was thought to always be detrimental to the host …
human disease and tissue damage, and was thought to always be detrimental to the host …
Self-assembled peptide nanostructures: the design of molecular building blocks and their technological utilization
E Gazit - Chemical Society Reviews, 2007 - pubs.rsc.org
In this tutorial review the process and applications of peptide self-assembly into nanotubes,
nanospheres, nanofibrils, nanotapes, and other ordered structures at the nano-scale are …
nanospheres, nanofibrils, nanotapes, and other ordered structures at the nano-scale are …
Bacterial adhesins in host-microbe interactions
KA Kline, S Fälker, S Dahlberg, S Normark… - Cell host & …, 2009 - cell.com
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express
adhesive molecules on their surfaces that promote interaction with host cell receptors or with …
adhesive molecules on their surfaces that promote interaction with host cell receptors or with …
The gut-brain axis in multiple sclerosis. Is its dysfunction a pathological trigger or a consequence of the disease?
B Parodi, N Kerlero de Rosbo - Frontiers in immunology, 2021 - frontiersin.org
A large and expending body of evidence indicates that the gut-brain axis likely plays a
crucial role in neurological diseases, including multiple sclerosis (MS). As a whole, the gut …
crucial role in neurological diseases, including multiple sclerosis (MS). As a whole, the gut …