Systematic review of the concentrations of oligosaccharides in human milk

S Thurl, M Munzert, G Boehm, C Matthews… - Nutrition …, 2017 - academic.oup.com
Context Oligosaccharides are the third largest solid component in human milk. These
diverse compounds are thought to have numerous beneficial functions in infants, including …

The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists

S Thomas, J Izard, E Walsh, K Batich… - Cancer research, 2017 - AACR
Humans consider themselves discrete autonomous organisms, but recent research is
rapidly strengthening the appreciation that associated microorganisms make essential …

Effects of infant formula with human milk oligosaccharides on growth and morbidity: a randomized multicenter trial

G Puccio, P Alliet, C Cajozzo, E Janssens… - Journal of pediatric …, 2017 - journals.lww.com
Objectives: The aim of the study was to evaluate the effects of infant formula supplemented
with 2 human milk oligosaccharides (HMOs) on infant growth, tolerance, and morbidity …

Immunological effects of human milk oligosaccharides

V Triantis, L Bode, RJJ Van Neerven - Frontiers in pediatrics, 2018 - frontiersin.org
Human milk oligosaccharides (HMOs) comprise a group of structurally complex,
unconjugated glycans that are highly abundant in human milk. HMOs are minimally digested …

Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants

ZT Lewis, SM Totten, JT Smilowitz, M Popovic, E Parker… - Microbiome, 2015 - Springer
Background Individuals with inactive alleles of the fucosyltransferase 2 gene (FUT2; termed
the 'secretor'gene) are common in many populations. Some members of the genus …

Human milk oligosaccharides influence neonatal mucosal and systemic immunity

SM Donovan, SS Comstock - Annals of Nutrition and Metabolism, 2016 - karger.com
The immune system of the infant is functionally immature and naïve. Human milk contains
bioactive proteins, lipids, and carbohydrates that protect the newborn and stimulate innate …

Human milk glycans protect infants against enteric pathogens

DS Newburg, GM Ruiz-Palacios, AL Morrow - Annu. Rev. Nutr., 2005 - annualreviews.org
▪ Abstract Breastfed infants have lower morbidity and mortality due to diarrhea than those fed
artificially. This had been attributed primarily to the secretory antibodies and prebiotic factors …

Human milk oligosaccharides: potential therapeutic aids for allergic diseases

I Tarrant, BB Finlay - Trends in Immunology, 2023 - cell.com
Human milk oligosaccharides: potential therapeutic aids for allergic diseases: Trends in
Immunology Skip to Main Content Advertisement Trends in Immunology This journal offers …

Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes

ZT Yu, C Chen, DS Newburg - Glycobiology, 2013 - academic.oup.com
Human milk oligosaccharides (HMOS) are not digested in the proximal intestine. In distal
intestine, HMOS collectively modify the microbiota, but the response of individual bacteria to …

Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides

DA Sela, DA Mills - Trends in microbiology, 2010 - cell.com
As the sole nutrition provided to infants, bioactive molecules dissolved in milk influence the
development of our gut microbiota. Accordingly, human milk oligosaccharides (HMOs) are …