The transition from genomics to phenomics in personalized population health
Modern health care faces several serious challenges, including an ageing population and
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …
Big data's role in precision public health
S Dolley - Frontiers in public health, 2018 - frontiersin.org
Precision public health is an emerging practice to more granularly predict and understand
public health risks and customize treatments for more specific and homogeneous …
public health risks and customize treatments for more specific and homogeneous …
Obesity and diabetes in Pacific Islanders: the current burden and the need for urgent action
NL Hawley, ST McGarvey - Current diabetes reports, 2015 - Springer
Non-communicable diseases (NCDs) now account for more than 36 million deaths each
year; many of which are premature. Pacific Islanders are some of the worst afflicted by …
year; many of which are premature. Pacific Islanders are some of the worst afflicted by …
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
X Liu, W Si, L He, J Yang, Y Peng, J Ren… - Signal transduction and …, 2021 - nature.com
The scope and variety of the metabolic intermediates from the mitochondrial tricarboxylic
acid (TCA) cycle that are engaged in epigenetic regulation of the chromatin function in the …
acid (TCA) cycle that are engaged in epigenetic regulation of the chromatin function in the …
Epigenetics analysis and integrated analysis of multiomics data, including epigenetic data, using artificial intelligence in the era of precision medicine
To clarify the mechanisms of diseases, such as cancer, studies analyzing genetic mutations
have been actively conducted for a long time, and a large number of achievements have …
have been actively conducted for a long time, and a large number of achievements have …
The promise for histone methyltransferase inhibitors for epigenetic therapy in clinical oncology: a narrative review
Epigenetic processes are essential for normal development and the maintenance of tissue-
specific gene expression in mammals. Changes in gene expression and malignant cellular …
specific gene expression in mammals. Changes in gene expression and malignant cellular …
Epi-drugs in heart failure
Unveiling the secrets of genome's flexibility does not only foster new research in the field,
but also gives rise to the exploration and development of novel epigenetic-based therapies …
but also gives rise to the exploration and development of novel epigenetic-based therapies …
Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications
A Bhargava, A Shukla, N Bunkar, R Shandilya… - Environmental …, 2019 - Elsevier
Exposure to ultrafine particulate matter (PM0. 1) is positively associated with the etiology of
different acute and chronic disorders; however, the in-depth biological imprints that link …
different acute and chronic disorders; however, the in-depth biological imprints that link …
A systematic review of progress toward unlocking the power of epigenetics in NSCLC: Latest updates and perspectives
A Sulewska, L Pilz, C Manegold, R Ramlau… - Cells, 2023 - mdpi.com
Epigenetic research has the potential to improve our understanding of the pathogenesis of
cancer, specifically non-small-cell lung cancer, and support our efforts to personalize the …
cancer, specifically non-small-cell lung cancer, and support our efforts to personalize the …
[BOOK][B] Global health: An introduction to current and future trends
K McCracken, DR Phillips - 2017 - taylorfrancis.com
Global Health continues to provide readers with a comprehensive, up-to-date and thought-
provoking outline and understanding of the constantly evolving global health landscape. In …
provoking outline and understanding of the constantly evolving global health landscape. In …