The Nrf2 transcription factor governs the expression of hundreds genes involved in cell
defense against oxidative stress, the hallmark of numerous diseases such as …

Skin cancers are by far the most common malignancy of humans, particularly in the white
population. The growing incidence of cutaneous malignancies has heralded the need for …

A dominant area of antibody research is the extension of the use of this mighty experimental
and therapeutic tool for the specific detection of molecules for diagnostics, visualization, and …

Despite the considerable progress in understanding the biology of human cancer and
technological advancement in drug discovery, treatment failure remains an inevitable …

Epidermal growth factor receptor (EGFR) is an integral surface protein mediating cellular
response to a number of growth factors. Its overexpression and increased activation due to …

The book examines the design, application, and utilization of devices, techniques, and
technologies critical to research at the atomic, molecular, and macromolecular levels …

The conventional chemotherapeutic treatment of malignant melanoma still remains poorly
efficient in most cases. Thus the use of specific features of these tumors for development of …

The presence of Auger electrons (AE) among the decay products of a number of
radionuclides makes these radionuclides an attractive means for treating cancer because …

Gamma-ray emitting 111In, which is extensively used for imaging, is also a source of short-
range Auger electrons (AE). While exhibiting negligible effect outside cells, these AE …

Abstract Introduction Modular nanotransporters (MNTs) are vehicles designed to transport
drugs from the cell surface via receptor-mediated endocytosis and endosomal escape to …