[HTML][HTML] Toward a comprehensive profiling of alternative splicing proteoform structures, interactions and functions
The mRNA splicing machinery has been estimated to generate 100,000 known protein-
coding transcripts for 20,000 human genes (Ensembl, Sept. 2024). However, this set is …
coding transcripts for 20,000 human genes (Ensembl, Sept. 2024). However, this set is …
Foundation models for bioinformatics
Z Chen, L Wei, G Gao - Quantitative Biology, 2024 - Wiley Online Library
Transformer‐based foundation models such as ChatGPTs have revolutionized our daily life
and affected many fields including bioinformatics. In this perspective, we first discuss about …
and affected many fields including bioinformatics. In this perspective, we first discuss about …
Identification, characterization, and design of plant genome sequences using deep learning
Z Wang, H Yuan, J Yan, J Liu - The Plant Journal, 2024 - Wiley Online Library
Due to its excellent performance in processing large amounts of data and capturing complex
non‐linear relationships, deep learning has been widely applied in many fields of plant …
non‐linear relationships, deep learning has been widely applied in many fields of plant …
Transformer model generated bacteriophage genomes are compositionally distinct from natural sequences
J Ratcliff - NAR Genomics and Bioinformatics, 2024 - academic.oup.com
Novel applications of language models in genomics promise to have a large impact on the
field. The megaDNA model is the first publicly available generative model for creating …
field. The megaDNA model is the first publicly available generative model for creating …
Artificial Intelligence Applications in Genomics
R Nagarajan, C Wang… - Advances in …, 2024 - advancesinmolecularpathology.com
Several factors have contributed to the rapid growth of genomic data, including the
significant reduction in high-throughput sequencing costs, the availability of scalable and …
significant reduction in high-throughput sequencing costs, the availability of scalable and …