AMP-activated protein kinase: An energy sensor and survival mechanism in the reinstatement of metabolic homeostasis

A Sharma, SK Anand, N Singh, UN Dwivedi… - Experimental cell …, 2023 - Elsevier
Cells are programmed to favorably respond towards the nutrient availability by adapting
their metabolism to meet energy demands. AMP-activated protein kinase (AMPK) is a highly …

Obesogens: a unifying theory for the global rise in obesity

JJ Heindel, RH Lustig, S Howard… - International Journal of …, 2024 - nature.com
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …

Sex difference in human diseases: mechanistic insights and clinical implications

Y Shi, J Ma, S Li, C Liu, Y Liu, J Chen, N Liu… - Signal transduction and …, 2024 - nature.com
Sex characteristics exhibit significant disparities in various human diseases, including
prevalent cardiovascular diseases, cancers, metabolic disorders, autoimmune diseases …

Plastic Food Packaging from Five Countries Contains Endocrine-and Metabolism-Disrupting Chemicals

S Stevens, M McPartland, Z Bartosova… - Environmental …, 2024 - ACS Publications
Plastics are complex chemical mixtures of polymers and various intentionally and
nonintentionally added substances. Despite the well-established links between certain …

Ultra-processed food consumption in UK adolescents: Distribution, trends, and sociodemographic correlates using the National Diet and Nutrition Survey 2008/09 to …

IY Chavez-Ugalde, F de Vocht, R Jago… - European Journal of …, 2024 - Springer
Purpose We quantified levels of ultra-processed food (UPF) consumption and investigated
consumption patterns in a representative sample of UK adolescents. Methods We used data …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

The multifaceted role of sodium nitroprusside in plants: Crosstalk with phytohormones under normal and stressful conditions

F Ullah, S Saqib, W Khan, A Ayaz, A Batool… - Plant Growth …, 2024 - Springer
Through intricate interactions with phytohormones, sodium nitroprusside (SNP), a nitric
oxide (NO) donor, has a variety of impacts on plant physiology. This comprehensive review …

Glucagon‐like peptide agonists for weight management in antipsychotic‐induced weight gain: A systematic review and meta‐analysis

M Bak, B Campforts, P Domen… - Acta Psychiatrica …, 2024 - Wiley Online Library
Introduction Managing body weight in patients with antipsychotic‐induced weight gain
(AIWG) is challenging. Besides lifestyle interventions, pharmacological interventions may …

Mitochondrial energy metabolism in the regulation of thermogenic brown fats and human metabolic diseases

Y Takeda, Y Harada, T Yoshikawa, P Dai - International Journal of …, 2023 - mdpi.com
Brown fats specialize in thermogenesis by increasing the utilization of circulating blood
glucose and fatty acids. Emerging evidence suggests that brown adipose tissue (BAT) …

Research progress on drugs for diabetes based on insulin receptor/insulin receptor substrate

J Su, L Tang, Y Luo, J Xu, S Ouyang - Biochemical Pharmacology, 2023 - Elsevier
The number of people with diabetes worldwide is increasing annually, resulting in a serious
economic burden. Insulin resistance is a major pathology in the early onset of diabetes …