The oligometastatic paradigm implies that patients who develop a small number of
metastatic lesions might achieve long-term survival if all these lesions are ablated with …

Leukocytes and their soluble mediators play important regulatory roles in all aspects of solid
tumor development. While immunotherapeutic strategies have conceptually held clinical …

Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal
tumors of the gastrointestinal tract. Neoplastic GIST cells seem to arise from a common …

PURPOSE: To analyze the long-term survival and tumor control outcomes after stereotactic
body radiotherapy (SBRT) for metastases limited in number and extent. METHODS AND …

BACKGROUND: A subset of patients with metastatic cancer in limited organs may benefit
from metastasis‐directed therapy. The authors investigated whether patients with limited …

Background Stage IV non–small-cell lung cancer (NSCLC) patients with oligometastases (<
5 metastatic lesions) may experience long-term survival when all macroscopic tumor sites …

Purpose: Stereotactic body radiotherapy (SBRT) is often used to treat patients with
oligometastases (OM). Yet, patterns of SBRT practice for OM are unknown. Therefore, we …

Thetermoligometastases, introducedin19951 anddetailedmore recently, 2 describes an
intermediate state of cancer spread between localized disease and widespread metastases …

In addition to inducing lethal DNA damage in tumor and stromal cells, radiation can alter the
interactions of tumor cells with their microenvironment. Recent technological advances in …

Background Radiotherapy is increasingly used to treat oligometastatic patients. We sought
to identify prognostic criteria in oligometastatic patients undergoing definitive …