Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY **ang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Exosomal circRNA: emerging insights into cancer progression and clinical application potential

F Zhang, J Jiang, H Qian, Y Yan, W Xu - Journal of Hematology & …, 2023 - Springer
Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …

Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment

Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …

Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration

Q Wu, L Hu, R Yan, J Shi, H Gu, Y Deng, R Jiang… - Bone Research, 2022 - nature.com
The restoration of bone defects caused by osteoporosis remains a challenge for surgeons.
Strontium ranelate has been applied in preventative treatment approaches due to the …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Exosome-derived circTRPS1 promotes malignant phenotype and CD8+ T cell exhaustion in bladder cancer microenvironments

C Yang, S Wu, Z Mou, Q Zhou, X Dai, Y Ou, X Chen… - Molecular Therapy, 2022 - cell.com
Circular RNAs (circRNAs) play critical roles in different diseases. Exosomes are important
intermediates of intercellular communication. While both have been widely reported in …

Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications

XH Tang, T Guo, XY Gao, XL Wu, XF **ng, JF Ji, ZY Li - Molecular cancer, 2021 - Springer
Exosomes are a subpopulation of the tumour microenvironment (TME) that transmit various
biological molecules to promote intercellular communication. Exosomes are derived from …

The role of exosomes in liquid biopsy for cancer diagnosis and prognosis prediction

S Li, M Yi, B Dong, X Tan, S Luo… - International journal of …, 2021 - Wiley Online Library
Liquid biopsy is a revolutionary strategy in cancer diagnosis and prognosis prediction, which
is used to analyze cancer cells or cancer‐derived products through biofluids such as blood …

CircOGDH is a penumbra biomarker and therapeutic target in acute ischemic stroke

Y Liu, Y Li, J Zang, T Zhang, Y Li, Z Tan, D Ma… - Circulation …, 2022 - Am Heart Assoc
Background: Acute ischemic stroke (AIS) is a leading cause of disability and mortality
worldwide. Prediction of penumbra existence after AIS is crucial for making decision on …

[HTML][HTML] The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy

J Li, G Zhang, CG Liu, X **ang, MTN Le, G Sethi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Exosomes are multifunctional regulators of intercellular communication by carrying various
messages under both physiological and pathological status of cancer patients …