Hypertensive disorders of pregnancy, an umbrella term that includes preexisting and
gestational hypertension, preeclampsia, and eclampsia, complicate up to 10% of …

Preeclampsia (PE) is a pregnancy-specific syndrome and one of the leading causes of
preterm birth, neonatal and maternal morbidity and mortality. This disease is characterized …

Studies over the last decade have provided exciting new insights into potential mechanisms
underlying the pathogenesis of preeclampsia. The initiating event in preeclampsia is …

The maternal microbiome is recognized as a key determinant of a range of important
maternal and child health outcomes, and together with perinatal factors influences the infant …

Background: Prior meta-analyses report a 2-to 4-fold increased risk of later cardiovascular
disease among women with a history of hypertensive disorders of pregnancy (HDP). Given …

Normal pregnancy is associated with reductions in total vascular resistance and arterial
pressure possibly due to enhanced endothelium-dependent vascular relaxation and …

Background The prevalence of pregnancy-induced hypertension in Ethiopia ranges from 2.2
to 18.3%. However, so far little is known about the adverse perinatal outcomes of pregnancy …

Studies during the past decade have provided a better understanding of the potential
mechanisms responsible for the pathogenesis of preeclampsia. The initiating event in …

Preeclampsia is defined as new onset hypertension with proteinuria during pregnancy. It
affects approximately 5% of pregnancies in the US with a subset of those progressing into …

Inflammatory cytokines such as tumor necrosis factor (TNF)-α are elevated in preeclamptic
women and are thought to be an important link between placental ischemia and endothelial …